SCHEMBL16749047

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16749046	0.93	KDM1A (0.42)	KDM1AALDH1A1KMT2ALMNAMEN1
	SCHEMBL16749144	0.89	ALDH1A1 (0.38)	KDM1AALDH1A1KMT2ALMNAMEN1
	SCHEMBL20126330	0.88	ALDH1A1 (0.44)	KDM1AALDH1A1KMT2AMEN1MAPT
	SCHEMBL17931282	0.87	ESR2 (0.40)	KDM1AALDH1A1KMT2ALMNAMEN1
	SCHEMBL16749135	0.86	KCNH2 (0.40)	KDM1AESR2KCNH2
	SCHEMBL16749142	0.86	KDM1A (0.38)	KDM1AALDH1A1KMT2ALMNAMEN1
	SCHEMBL18931580	0.86	KDM1A (0.32)	KDM1A
	SCHEMBL20126102	0.85	NISCH (0.39)	ALDH1A1KMT2ALMNAMEN1MAPT
	SCHEMBL25259299	0.83	CYP19A1 (0.38)	KDM1AALDH1A1KMT2ALMNAMEN1
	SCHEMBL6023464	0.83	ESR2 (0.52)	KDM1AESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.