Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16749134 | 0.90 | TSHR (0.40) | TSHRALDH1A1NPSR1PPARAGAA | |
| SCHEMBL16749051 | 0.87 | TSHR (0.44) | TSHRALDH1A1NPSR1GAAKDM4E | |
| SCHEMBL16749056 | 0.82 | TSHR (0.34) | TSHRALDH1A1NPSR1PPARAPPARG | |
| SCHEMBL818726 | 0.80 | TSHR (0.36) | TSHRGAAKDM4ELMNARECQL | |
| SCHEMBL10621109 | 0.80 | TSHR (0.36) | TSHRGAAKDM4ELMNARECQL | |
| SCHEMBL16749057 | 0.76 | TSHR (0.40) | TSHRALDH1A1NPSR1GAAKDM4E | |
| SCHEMBL11527432 | 0.75 | ALDH1A1 (0.44) | TSHRALDH1A1NPSR1GAAKDM4E | |
| SCHEMBL6701258 | 0.73 | TSHR (0.39) | TSHRALDH1A1NPSR1GAAKDM4E | |
| SCHEMBL15707671 | 0.73 | ALDH1A1 (0.39) | TSHRALDH1A1GAA | |
| SCHEMBL98369 | 0.73 | SIGMAR1 (0.42) | TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160289189-A1 | PIPERIDINE DERIVATIVE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC CORPORATION (JP) | 2016-10-06 | — | — | US | disclosed |
| US-20160289189-A1 | PIPERIDINE DERIVATIVE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC CORPORATION (JP) | 2016-10-06 | — | — | US | disclosed |
| EP-3072885-A1 | PIPERIDINE DERIVATIVE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC Corporation (JP) | 2016-09-28 | — | — | EP | disclosed |
| WO-2015076077-A1 | PIPERIDINE DERIVATIVE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC株式会社 | 2015-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160289189-A1 | PIPERIDINE DERIVATIVE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | PLD1, DRD1, CCND1 | TSHR 3337/4885ALDH1A1 256/4885NPSR1 573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.