Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 11/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 9/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1673555 | 1.00 | NR1H2 (0.50) | NR1H2NR1H3GPR119 | |
| SCHEMBL1673505 | 0.86 | GPR119 (0.48) | NR1H2NR1H3GPR119 | |
| SCHEMBL1673508 | 0.86 | GPR119 (0.48) | NR1H2NR1H3GPR119 | |
| SCHEMBL27629059 | 0.85 | NR1H2 (0.45) | NR1H2NR1H3GPR119 | |
| SCHEMBL1673585 | 0.80 | NR1H2 (0.46) | NR1H2NR1H3GPR119 | |
| SCHEMBL1673586 | 0.80 | NR1H2 (0.46) | NR1H2NR1H3GPR119 | |
| SCHEMBL83999 | 0.80 | GPR119 (0.48) | NR1H2NR1H3GPR119 | |
| SCHEMBL22772313 | 0.77 | NR1H2 (0.47) | NR1H2NR1H3GPR119 | |
| SCHEMBL83834 | 0.76 | NR1H2 (0.59) | NR1H2NR1H3 | |
| SCHEMBL521801 | 0.76 | NR1H2 (0.49) | NR1H2NR1H3GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308854-A1 | 2,3,6-trisubstituted-4-pyrimidone derivatives | Sanofi-Aventis (FR) | 2011-04-13 | — | — | EP | disclosed |