Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16749144 | 0.95 | ALDH1A1 (0.38) | ALDH1A1NPSR1GAAKDM4ELMNA | |
| SCHEMBL20126288 | 0.89 | SPHK1 (0.52) | ALDH1A1KDM4ELMNASPHK1 | |
| SCHEMBL16749146 | 0.88 | ALDH1A1 (0.36) | ALDH1A1NPSR1GAAKDM4ELMNA | |
| SCHEMBL16749046 | 0.88 | KDM1A (0.42) | ALDH1A1NPSR1GAAKDM4ELMNA | |
| SCHEMBL18931609 | 0.87 | ALDH1A1 (0.34) | ALDH1A1NPSR1GAAKDM4ELMNA | |
| SCHEMBL20126102 | 0.87 | NISCH (0.39) | ALDH1A1NPSR1GAAKDM4ELMNA | |
| SCHEMBL18931587 | 0.83 | ALDH1A1 (0.33) | ALDH1A1NPSR1GAAKDM4ELMNA | |
| SCHEMBL19998064 | 0.83 | ALDH1A1 (0.32) | ALDH1A1NPSR1GAAKDM4ELMNA | |
| SCHEMBL16749047 | 0.82 | KDM1A (0.39) | ALDH1A1NPSR1GAAKDM4ELMNA | |
| SCHEMBL20126355 | 0.82 | ALDH1A1 (0.33) | ALDH1A1NPSR1GAAKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160289189-A1 | PIPERIDINE DERIVATIVE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC CORPORATION (JP) | 2016-10-06 | — | — | US | disclosed |
| US-20160289189-A1 | PIPERIDINE DERIVATIVE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC CORPORATION (JP) | 2016-10-06 | — | — | US | disclosed |
| EP-3072885-A1 | PIPERIDINE DERIVATIVE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC Corporation (JP) | 2016-09-28 | — | — | EP | disclosed |
| WO-2015076077-A1 | PIPERIDINE DERIVATIVE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC株式会社 | 2015-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160289189-A1 | PIPERIDINE DERIVATIVE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | PLD1, DRD1, CCND1 | ALDH1A1 256/4885NPSR1 573/4885GAA 4581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.