⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18721171 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL17924744 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL17924726 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL17924729 | 0.98 | — | — | |
| SCHEMBL18826932 | 0.89 | ALOX5 (0.34) | — | |
| SCHEMBL17933284 | 0.88 | LMNA (0.37) | — | |
| Hydrochloric Acid SCHEMBL17924725 | 0.86 | LMNA (0.35) | — | |
| Hydrochloric Acid SCHEMBL17924723 | 0.86 | LMNA (0.35) | — | |
| Hydrochloric Acid SCHEMBL17924748 | 0.86 | LMNA (0.35) | — | |
| SCHEMBL16749354 | 0.82 | UGT2B7 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071564-B1 | DIHYDROPYRIMIDINE COMPOUNDS AND THEIR APPLICATION IN PHARMACEUTICALS | SUNSHINE LAKE PHARMA CO LTD (CN) | 2020-08-05 | — | — | EP | disclosed |
| EP-3074392-B1 | PROCESSES FOR PREPARING DIHYDROPYRIMIDINE DERIVATIVES AND INTERMEDIATES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2019-04-03 | — | — | EP | disclosed |
| EP-3074394-B1 | PROCESSES FOR PREPARING DIHYDROPYRIMIDINE DERIVATIVES AND INTERMEDIATES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2019-02-20 | — | — | EP | disclosed |
| US-9643962-B2 | Processes for preparing dihydropyrimidine derivatives and intermediates thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-05-09 | — | — | US | disclosed |
| US-9617252-B2 | Processes for preparing dihydropyrimidine derivatives and intermediates thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-04-11 | — | — | US | disclosed |
| US-9573941-B2 | Processes for preparing dihydropyrimidine derivatives and intermediates thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-02-21 | — | — | US | disclosed |
| US-9498479-B2 | Dihydropyrimidine compounds and their application in pharmaceuticals | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-11-22 | — | — | US | disclosed |
| US-20160264563-A1 | PROCESSES FOR PREPARING DIHYDROPYRIMIDINE DERIVATIVES AND INTERMEDIATES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-09-15 | — | — | US | disclosed |
| US-20160264562-A1 | PROCESSES FOR PREPARING DIHYDROPYRIMIDINE DERIVATIVES AND INTERMEDIATES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-09-15 | — | — | US | disclosed |
| US-20160244438-A1 | PROCESSES FOR PREPARING DIHYDROPYRIMIDINE DERIVATIVES AND INTERMEDIATES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-08-25 | — | — | US | disclosed |
| US-20160206616-A1 | DIHYDROPYRIMIDINE COMPOUNDS AND THEIR APPLICATION IN PHARMACEUTICALS | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-07-21 | — | — | US | disclosed |
| WO-2015078392-A1 | PROCESSES FOR PREPARING DIHYDROPYRIMIDINE DERIVATIVES AND INTERMEDIATES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-06-04 | — | — | WO | disclosed |
| WO-2015078391-A1 | PROCESSES FOR PREPARING DIHYDROPYRIMIDINE DERIVATIVES AND INTERMEDIATES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-06-04 | — | — | WO | disclosed |
| WO-2015078393-A1 | PROCESSES FOR PREPARING DIHYDROPYRIMIDINE DERIVATIVES AND INTERMEDIATES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-06-04 | — | — | WO | disclosed |
| WO-2015074546-A1 | DIHYDROPYRIMIDINE COMPOUNDS AND THEIR APPLICATION IN PHARMACEUTICALS | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-05-28 | — | — | WO | disclosed |