SCHEMBL16751998

SCHEMBL16751998

C=C(C)C(=O)c1ccc(Oc2ccc(C(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ELANE P08246 5/20 0.64
SRD5A2 P31213 4/20 0.59
MAPT P10636 2/20 0.59
ACACB O00763 1/20 0.55
ACACA Q13085 1/20 0.55
POLB P06746 1/20 0.54
CES2 O00748 1/20 0.51
CES1 P23141 1/20 0.51
HPGD P15428 1/20 0.48
RAB9A P51151 1/20 0.48
ALDH1A1 P00352 1/20 0.48
HTT P42858 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
PARP10 Q53GL7 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1887295 0.89 ELANE (0.61) ELANESRD5A2MAPTCES2CES1
SCHEMBL9419497 0.84 SRD5A2 (0.80) ELANESRD5A2POLBALDH1A1PARP10
SCHEMBL9809047 0.84 SRD5A2 (0.80) ELANESRD5A2POLBALDH1A1PARP10
SCHEMBL124917 0.84 SRD5A2 (0.80) ELANESRD5A2POLBALDH1A1PARP10
SCHEMBL28938440 0.84 SRD5A2 (0.80) ELANESRD5A2POLBALDH1A1PARP10
SCHEMBL21935942 0.82 MAPT (0.73) ELANESRD5A2MAPTACACBACACA
SCHEMBL234249 0.82 SRD5A2 (0.84) ELANESRD5A2POLBALDH1A1PARP10
SCHEMBL22415445 0.82 SRD5A2 (0.84) ELANESRD5A2POLBALDH1A1PARP10
SCHEMBL1069817 0.82 SRD5A2 (0.84) ELANESRD5A2POLBALDH1A1PARP10
SCHEMBL26759067 0.82 SRD5A2 (0.84) ELANESRD5A2POLBALDH1A1PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11624008-B2 Composition useful as a pressure sensitive adhesive, its use and adhesive articles comprising it IGM RESINS ITALIA S.R.L (IT) 2023-04-11 US disclosed
US-20210292454-A1 COMPOSITION USEFUL AS A PRESSURE SENSITIVE ADHESIVE, ITS USE AND ADHESIVE ARTICLES COMPRISING IT IGM RESINS ITALIA S.R.L (IT) 2021-09-23 US disclosed
US-20210130520-A1 COMPOSITION USEFUL AS A PRESSURE SENSITIVE ADHESIVE, ITS USE AND ADHESIVE ARTICLES COMPRISING IT IGM RESINS ITALIA S.R.L. (IT) 2021-05-06 US disclosed
WO-2018127332-A1 COMPOSITION USEFUL AS A PRESSURE SENSITIVE ADHESIVE, ITS USE AND ADHESIVE ARTICLES COMPRISING IT IGM RESINS ITALIA S.R.L. (IT) 2018-07-12 WO disclosed
US-9932499-B2 UV-curable composition and pressure sensitive adhesive having breathability derived therefrom, as well as method for manufacturing the same ICAP-SIRA S.p.A. (IT) 2018-04-03 US disclosed
US-9932499-B2 UV-curable composition and pressure sensitive adhesive having breathability derived therefrom, as well as method for manufacturing the same ICAP-SIRA S.p.A. (IT) 2018-04-03 US disclosed
US-9932499-B2 UV-curable composition and pressure sensitive adhesive having breathability derived therefrom, as well as method for manufacturing the same ICAP-SIRA S.p.A. (IT) 2018-04-03 US disclosed
EP-2858969-B1 COPOLYMERIZABLE PHOTOINITIATORS IGM RESINS ITALIA SRL (IT) 2016-09-07 EP disclosed
US-9394455-B2 Copolymerizable photoinitiators IGM RESINS ITALIA S.R.L. (IT) 2016-07-19 US disclosed
US-9394455-B2 Copolymerizable photoinitiators IGM RESINS ITALIA S.R.L. (IT) 2016-07-19 US disclosed
US-9394455-B2 Copolymerizable photoinitiators IGM RESINS ITALIA S.R.L. (IT) 2016-07-19 US disclosed
EP-2878606-B1 UV-curable composition and pressure sensitive adhesive having breathability derived therefrom, as well as method for manufacturing the same ICAP SIRA S P A (IT) 2015-08-05 EP disclosed
US-20150175830-A1 COPOLYMERIZABLE PHOTOINITIATORS ELIOS S.R.L. (IT) 2015-06-25 US disclosed
US-20150175830-A1 COPOLYMERIZABLE PHOTOINITIATORS ELIOS S.R.L. (IT) 2015-06-25 US disclosed
US-20150175830-A1 COPOLYMERIZABLE PHOTOINITIATORS ELIOS S.R.L. (IT) 2015-06-25 US disclosed
US-20150152297-A1 UV-curable composition and pressure sensitive adhesive having breathability derived therefrom, as well as method for manufacturing the same ICAP-SIRA S.p.A. (IT) 2015-06-04 US disclosed
US-20150152297-A1 UV-curable composition and pressure sensitive adhesive having breathability derived therefrom, as well as method for manufacturing the same ICAP-SIRA S.p.A. (IT) 2015-06-04 US disclosed
US-20150152297-A1 UV-curable composition and pressure sensitive adhesive having breathability derived therefrom, as well as method for manufacturing the same ICAP-SIRA S.p.A. (IT) 2015-06-04 US disclosed
EP-2878606-A1 UV-curable composition and pressure sensitive adhesive having breathability derived therefrom, as well as method for manufacturing the same ICAP-SIRA S.p.A. (IT) 2015-06-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150175830-A1 COPOLYMERIZABLE PHOTOINITIATORS NR2E3, NR0B1, NR0B2 ELANE 3715/4885SRD5A2 110/4885MAPT 3057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.