Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 5/20 | 0.42 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL10743359 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL11658894 | 0.95 | CA4 (0.50) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL8805172 | 0.95 | CA1 (0.50) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL4235385 | 0.94 | — | — | |
| Bicarbonate SCHEMBL8776836 | 0.94 | — | — | |
| Bicarbonate SCHEMBL17309672 | 0.89 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL7608551 | 0.89 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL1701669 | 0.89 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL11309619 | 0.89 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL10697570 | 0.89 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3077472-B1 | METHODS TO RECOVER CESIUM/RUBIDIUM FORMATE FROM A MIXED ALKALI METAL FORMATE BLEND, AND METHOD FOR PREPARING CESIUM/RUBIDIUM HYDROXIDE | SINOMINE RESOURCES US INC (US) | 2020-08-12 | — | — | EP | disclosed |
| CN-105960444-B | Method for recovering cesium formate from mixed alkali metal formate blends | 卡博特公司 | 2018-12-11 | — | — | CN | disclosed |
| US-9573821-B2 | Methods to recover cesium formate from a mixed alkali metal formate blend | CABOT CORPORATION (US) | 2017-02-21 | — | — | US | disclosed |
| US-20160355406-A1 | Methods To Recover Cesium Formate From A Mixed Alkali Metal Formate Blend | CABOT CORPORATION (US) | 2016-12-08 | — | — | US | disclosed |
| EP-3077472-A1 | METHODS TO RECOVER CESIUM FORMATE FROM A MIXED ALKALI METAL FORMATE BLEND | Cabot Corporation (US) | 2016-10-12 | — | — | EP | disclosed |
| US-9452966-B2 | Methods to recover cesium formate from a mixed alkali metal formate blend | CABOT CORPORATION (US) | 2016-09-27 | — | — | US | disclosed |
| CN-105960444-A | Method for recovering cesium formate from mixed alkali metal formate blends | 卡博特公司 | 2016-09-21 | — | — | CN | disclosed |
| WO-2015084416-A1 | METHODS TO RECOVER CESIUM FORMATE FROM A MIXED ALKALI METAL FORMATE BLEND | CABOT CORPORATION (US) | 2015-06-11 | — | — | WO | disclosed |
| US-20150152033-A1 | Methods To Recover Cesium Formate From A Mixed Alkali Metal Formate Blend | SINOMINE RESOURCES (US) INC. | 2015-06-04 | — | — | US | disclosed |