Glutamine

Glutamine

SCHEMBL1675508

NC(=O)CC[C@H](N)C(=O)O.NCC(=O)O.O=C(O)[C@@H]1CCCN1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC5A2

The experimentally established mechanism targets of Glutamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.50
BLM P54132 1/20 0.50
PMP22 Q01453 1/20 0.50
KMT2A Q03164 1/20 0.50
GSR P00390 2/20 0.40
GRM8 O00222 2/20 0.40
GRM6 O15303 2/20 0.40
GRM7 Q14831 2/20 0.40
GRM4 Q14833 2/20 0.40
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
CYP1A2 P05177 1/20 0.40
GRIK1 P39086 1/20 0.40
GRM5 P41594 1/20 0.40
GRIA1 P42261 1/20 0.40
GRIA2 P42262 1/20 0.40
GRIA3 P42263 1/20 0.40
SLC1A3 P43003 1/20 0.40
SLC1A2 P43004 1/20 0.40
SLC1A1 P43005 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamine SCHEMBL4298256 1.00 ALOX15 (0.50) ALOX15BLMPMP22KMT2AGSR
Glutamine SCHEMBL4412209 1.00 ALOX15 (0.50) ALOX15BLMPMP22KMT2AGSR
Glutamine SCHEMBL1675448 1.00 ALOX15 (0.50) ALOX15BLMPMP22KMT2AGSR
Glutamine SCHEMBL5800546 1.00 ALOX15 (0.50) ALOX15BLMPMP22KMT2AGSR
Glutamine SCHEMBL28774546 1.00 ALOX15 (0.50) ALOX15BLMPMP22KMT2AGSR
Glutamine SCHEMBL5307070 0.95 ALOX15 (0.45) ALOX15BLMPMP22KMT2AGSR
Glutamine SCHEMBL1675342 0.95 ALOX15 (0.45) ALOX15BLMPMP22KMT2AGSR
Glutamine SCHEMBL19031702 0.95 ALOX15 (0.45) ALOX15BLMPMP22KMT2AGSR
Glutamine SCHEMBL19031700 0.95 ALOX15 (0.45) ALOX15BLMPMP22KMT2AGSR
Glutamine SCHEMBL3442669 0.95 ALOX15 (0.45) ALOX15BLMPMP22KMT2AGSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1064010-A4 PEPTIDE COMPOSITIONS AND FORMULATIONS AND USE OF SAME CONNECTIVE TISSUE IMAGINEERING (US) 2004-10-06 EP claimed
EP-1064010-A1 PEPTIDE COMPOSITIONS AND FORMULATIONS AND USE OF SAME Mrs, Llc (US) 2001-01-03 EP claimed
WO-1999045941-A1 PEPTIDE COMPOSITIONS AND FORMULATIONS AND USE OF SAME MRS, LLC (US) 1999-09-16 WO claimed
CN-116042568-A Intein Crv Rpb2 variant, coding gene and application thereof in preparation of hexapeptide-nine 广州市乾相生物科技有限公司 2023-05-02 CN disclosed
EP-3334451-B1 COMPOSITION FOR THE TREATMENT OF JOINT CONDITIONS STOFFEL BERNARD (BE) 2020-10-28 EP disclosed
US-20190000874-A1 Composition for the Treatment of Joint Conditions NEWVEN SPRL (BE) 2019-01-03 US disclosed
EP-3334451-A1 COMPOSITION FOR THE TREATMENT OF JOINT CONDITIONS Stoffel, Bertrand (BE) 2018-06-20 EP disclosed
WO-2017025635-A1 COMPOSITION FOR THE TREATMENT OF JOINT CONDITIONS NEWVEN SPRL (BE) 2017-02-16 WO disclosed
US-9458197-B2 Elastin digest compositions and methods utilizing same HUMAN MATRIX SCIENCES, LLC (US) 2016-10-04 US disclosed
US-20150110755-A1 ELASTIN PRODUCING FIBROBLAST FORMULATIONS AND METHODS OF USING THE SAME NULASTIN, INC. 2015-04-23 US disclosed
US-20150004184-A1 ELASTIN DIGEST COMPOSITIONS AND METHODS UTILIZING SAME NULASTIN, INC. 2015-01-01 US disclosed
WO-2008148143-A1 DIAGNOSTICS IN A MONOPLEX/MULTIPLEX FORMAT UNIVERSITY OF WOLLONGONG (AU) 2008-12-11 WO disclosed
WO-2006081623-A1 DOUBLE-STRANDED OLIGONUCLEOTIDES AND USES THEREFOR THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 2006-08-10 WO disclosed
CN-1267149-C Composition and methods to improve neural outcome AUCKLAND UNISERVICES LTD (NZ) 2006-08-02 CN disclosed
US-6780848-B2 Use of GPE to protect glial cells or non-dopaminergic cells from death from neural injury or disease NeuronZ, Ltd. (NZ) 2004-08-24 US disclosed
US-20020013277-A1 Composition and methods to improve neural outcome ENDOCRINZ LIMITED (NZ) 2002-01-31 US disclosed
EP-0735894-A4 COMPOSITION AND METHODS TO IMPROVE NEURAL OUTCOME AUCKLAND UNISERVICES LTD (NZ) 1999-08-18 EP disclosed
CN-1142770-A Composition and methods to improve neural outcome AUCKLAND UNISERVICES LTD (NZ) 1997-02-12 CN disclosed
EP-0735894-A1 COMPOSITION AND METHODS TO IMPROVE NEURAL OUTCOME AUCKLAND UNISERVICES LIMITED (NZ) 1996-10-09 EP disclosed
WO-1995017204-A1 COMPOSITION AND METHODS TO IMPROVE NEURAL OUTCOME AUCKLAND UNISERVICES LIMITED (NZ) 1995-06-29 WO disclosed