Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glutamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GSR | P00390 | 2/20 | 0.40 |
| ▸ | GRM8 | O00222 | 2/20 | 0.40 |
| ▸ | GRM6 | O15303 | 2/20 | 0.40 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutamine SCHEMBL4412209 | 1.00 | ALOX15 (0.50) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL1675508 | 1.00 | ALOX15 (0.50) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL1675448 | 1.00 | ALOX15 (0.50) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL5800546 | 1.00 | ALOX15 (0.50) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL28774546 | 1.00 | ALOX15 (0.50) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL5307070 | 0.95 | ALOX15 (0.45) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL1675342 | 0.95 | ALOX15 (0.45) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL19031702 | 0.95 | ALOX15 (0.45) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL19031700 | 0.95 | ALOX15 (0.45) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL3442669 | 0.95 | ALOX15 (0.45) | ALOX15BLMPMP22KMT2AGSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9458197-B2 | Elastin digest compositions and methods utilizing same | HUMAN MATRIX SCIENCES, LLC (US) | 2016-10-04 | — | — | US | disclosed |
| US-20150004184-A1 | ELASTIN DIGEST COMPOSITIONS AND METHODS UTILIZING SAME | NULASTIN, INC. | 2015-01-01 | — | — | US | disclosed |
| US-8828927-B2 | Elastin digest compositions and methods utilizing same | HUMAN MATRIX SCIENCES, LLC (US) | 2014-09-09 | — | — | US | disclosed |
| US-20130295122-A1 | ELASTIN DIGEST COMPOSITIONS AND METHODS UTILIZING SAME | NULASTIN, INC. | 2013-11-07 | — | — | US | disclosed |
| US-8461113-B2 | Elastin digest compositions and methods utilizing same | HUMAN MATRIX SCIENCES, LLC (US) | 2013-06-11 | — | — | US | disclosed |
| US-20090286696-A1 | Double-Stranded Olidonucleotides and Uses Therefor | UNIVERSITY OF WOLLONGONG | 2009-11-19 | — | — | US | disclosed |
| US-20090281044-A1 | ELASTIN DIGEST COMPOSITIONS AND METHODS UTILIZING SAME | NULASTIN, INC. | 2009-11-12 | — | — | US | disclosed |
| WO-2008148143-A1 | DIAGNOSTICS IN A MONOPLEX/MULTIPLEX FORMAT | UNIVERSITY OF WOLLONGONG (AU) | 2008-12-11 | — | — | WO | disclosed |
| WO-2006081623-A1 | DOUBLE-STRANDED OLIGONUCLEOTIDES AND USES THEREFOR | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2006-08-10 | — | — | WO | disclosed |
| EP-1166650-B1 | Cheese flavor | SYMRISE GMBH & CO KG (DE) | 2005-09-07 | — | — | EP | disclosed |
| US-20020034570-A1 | Cheese flavoring | SYMRISE GMBH & CO. KG (DE) | 2002-03-21 | — | — | US | disclosed |
| EP-1166650-A2 | Cheese flavor | HAARMANN & REIMER GMBH (DE) | 2002-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286696-A1 | Double-Stranded Olidonucleotides and Uses Therefor | DNTT, ADAR, DUT | ALOX15 4201/4885BLM 1041/4885PMP22 4678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.