SCHEMBL16757633

SCHEMBL16757633

COCCN(CCC(=O)O)C(=O)CN(CCOC)C(=O)CN(CCOC)C(=O)CN

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.37
▸ HSD17B10 Q99714 1/20 0.34
▸ POLB P06746 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ ALDH2 P05091 1/20 0.33
▸ SLC6A2 P23975 1/20 0.32
▸ SLC6A4 P31645 1/20 0.32
▸ TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28087989 0.84 ALDH1A1 (0.37) ALDH1A1HSD17B10POLBL3MBTL1ALDH2
SCHEMBL19820850 0.80 POLB (0.35) ALDH1A1POLBL3MBTL1SLC6A2SLC6A4
SCHEMBL16757546 0.79 — —
SCHEMBL16757719 0.79 — —
SCHEMBL19820844 0.78 SLC6A2 (0.32) HSD17B10POLBL3MBTL1SLC6A2SLC6A4
SCHEMBL17636569 0.77 ALDH1A1 (0.48) ALDH1A1HSD17B10POLBL3MBTL1TSHR
SCHEMBL17636570 0.74 ALDH1A1 (0.55) ALDH1A1POLBL3MBTL1TSHR
SCHEMBL17636568 0.74 ALDH1A1 (0.61) ALDH1A1HSD17B10TSHR
SCHEMBL4432572 0.74 CA12 (0.39) ALDH1A1SLC6A2SLC6A4TSHR
SCHEMBL13702529 0.73 ALDH1A1 (0.38) ALDH1A1HSD17B10POLBL3MBTL1ALDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4592275-A2 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE Redwood Bioscience, Inc. (US) 2025-07-30 — — EP disclosed
EP-3074010-B1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE REDWOOD BIOSCIENCE INC (US) 2025-05-14 — — EP disclosed
US-12215080-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCE, INC. (US) 2025-02-04 — — US disclosed
CN-115504924-A Hydrazino-pyrrolo compounds and methods for forming conjugates 雷德伍德生物科技股份有限公司 2022-12-23 — — CN disclosed
CN-105744935-B Hydrazino-pyrrolo compounds and methods for forming conjugates 雷德伍德生物科技股份有限公司 2022-09-30 — — CN disclosed
US-20220153696-A1 Hydrazinyl-Pyrrolo Compounds and Methods for Producing a Conjugate ARES CAPITAL CORPORATION, AS COLLATERAL AGENT 2022-05-19 — — US disclosed
US-20220153696-A1 Hydrazinyl-Pyrrolo Compounds and Methods for Producing a Conjugate ARES CAPITAL CORPORATION, AS COLLATERAL AGENT 2022-05-19 — — US disclosed
US-11180451-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCE, INC. (US) 2021-11-23 — — US disclosed
US-11180451-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCE, INC. (US) 2021-11-23 — — US disclosed
US-20200317610-A1 Hydrazinyl-Pyrrolo Compounds and Methods for Producing a Conjugate ARES CAPITAL CORPORATION, AS COLLATERAL AGENT 2020-10-08 — — US disclosed
US-20170049907-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE CATALENT PHARMA SOLUTIONS, LLC 2017-02-23 — — US disclosed
US-9493413-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCE, INC. (US) 2016-11-15 — — US disclosed
US-9493413-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCE, INC. (US) 2016-11-15 — — US disclosed
US-9493413-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCE, INC. (US) 2016-11-15 — — US disclosed
EP-3074010-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE Redwood Bioscience, Inc. (US) 2016-10-05 — — EP disclosed
US-20150157736-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE R.P. SCHERER TECHNOLOGIES, LLC 2015-06-11 — — US disclosed
US-20150157736-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE R.P. SCHERER TECHNOLOGIES, LLC 2015-06-11 — — US disclosed
US-20150157736-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE R.P. SCHERER TECHNOLOGIES, LLC 2015-06-11 — — US disclosed
WO-2015081282-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE REDWOOD BIOSCIENCE, INC. (US) 2015-06-04 — — WO disclosed
WO-2015081282-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE REDWOOD BIOSCIENCE, INC. (US) 2015-06-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150157736-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE DNPEP, QPCT, PDS5A ALDH1A1 1538/4885HSD17B10 1242/4885POLB 3676/4885
US-20220153696-A1 Hydrazinyl-Pyrrolo Compounds and Methods for Producing a Conjugate DNPEP, QPCT, PDS5A ALDH1A1 1538/4885HSD17B10 1242/4885POLB 3676/4885
US-20170049907-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE DNPEP, QPCT, PDS5A ALDH1A1 1538/4885HSD17B10 1242/4885POLB 3676/4885
US-12215080-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate DNPEP, QPCT, PDS5A ALDH1A1 1538/4885HSD17B10 1242/4885POLB 3676/4885
US-11180451-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate DNPEP, QPCT, PDS5A ALDH1A1 1538/4885HSD17B10 1242/4885POLB 3676/4885
US-20200317610-A1 Hydrazinyl-Pyrrolo Compounds and Methods for Producing a Conjugate DNPEP, QPCT, PDS5A ALDH1A1 1538/4885HSD17B10 1242/4885POLB 3676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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