SCHEMBL16757546

SCHEMBL16757546

CC(C)(C)[Si](C)(C)OCCN(CCC(=O)O)C(=O)CN(CCO[Si](C)(C)C(C)(C)C)C(=O)CN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16757719 1.00 — —
SCHEMBL29975093 0.84 — —
SCHEMBL7139414 0.81 PHF8 (0.35) —
SCHEMBL16757633 0.79 ALDH1A1 (0.37) —
SCHEMBL19560799 0.79 CA14 (0.39) —
SCHEMBL6528981 0.78 ALDH1A1 (0.36) —
SCHEMBL29975113 0.78 CASP1 (0.31) —
SCHEMBL8707385 0.78 DUT (0.31) —
SCHEMBL16771761 0.75 — —
SCHEMBL16771799 0.75 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4592275-A2 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE Redwood Bioscience, Inc. (US) 2025-07-30 — — EP disclosed
EP-3074010-B1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE REDWOOD BIOSCIENCE INC (US) 2025-05-14 — — EP disclosed
US-12215080-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCE, INC. (US) 2025-02-04 — — US disclosed
US-12076411-B2 Anti-HER2 antibody-maytansine conjugates and methods of use thereof REDWOOD BIOSCIENCE, INC. (US) 2024-09-03 — — US disclosed
CN-105744935-B Hydrazino-pyrrolo compounds and methods for forming conjugates 雷德伍德生物科技股份有限公司 2022-09-30 — — CN disclosed
US-20220153696-A1 Hydrazinyl-Pyrrolo Compounds and Methods for Producing a Conjugate ARES CAPITAL CORPORATION, AS COLLATERAL AGENT 2022-05-19 — — US disclosed
US-20220153696-A1 Hydrazinyl-Pyrrolo Compounds and Methods for Producing a Conjugate ARES CAPITAL CORPORATION, AS COLLATERAL AGENT 2022-05-19 — — US disclosed
US-20220023440-A1 Anti-Her2 Antibody-Maytansine Conjugates and Methods of Use Thereof ARES CAPITAL CORPORATION, AS COLLATERAL AGENT 2022-01-27 — — US disclosed
US-20220023440-A1 Anti-Her2 Antibody-Maytansine Conjugates and Methods of Use Thereof ARES CAPITAL CORPORATION, AS COLLATERAL AGENT 2022-01-27 — — US disclosed
US-11180451-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCE, INC. (US) 2021-11-23 — — US disclosed
US-20170049907-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE CATALENT PHARMA SOLUTIONS, LLC 2017-02-23 — — US disclosed
US-9493413-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCE, INC. (US) 2016-11-15 — — US disclosed
US-9493413-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCE, INC. (US) 2016-11-15 — — US disclosed
EP-3074010-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE Redwood Bioscience, Inc. (US) 2016-10-05 — — EP disclosed
US-20150352225-A1 Anti-Her2 Antibody-Maytansine Conjugates and Methods of Use Thereof R.P. SCHERER TECHNOLOGIES, INC. 2015-12-10 — — US disclosed
US-20150352225-A1 Anti-Her2 Antibody-Maytansine Conjugates and Methods of Use Thereof R.P. SCHERER TECHNOLOGIES, INC. 2015-12-10 — — US disclosed
WO-2015187428-A1 ANTI-HER2 ANTIBODY-MAYTANSINE CONJUGATES AND METHODS OF USE THEREOF REDWOOD BIOSCIENCE, INC. (US) 2015-12-10 — — WO disclosed
US-20150157736-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE R.P. SCHERER TECHNOLOGIES, LLC 2015-06-11 — — US disclosed
US-20150157736-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE R.P. SCHERER TECHNOLOGIES, LLC 2015-06-11 — — US disclosed
WO-2015081282-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE REDWOOD BIOSCIENCE, INC. (US) 2015-06-04 — — WO disclosed
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