Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 6/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 6/20 | 0.36 |
| ▸ | HPGDS | O60760 | 4/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16757859 | 0.92 | CYP4F2 (0.36) | CYP4F2CYP4A11HPGDSGPR119SCN9A | |
| SCHEMBL16758058 | 0.92 | CYP4F2 (0.36) | CYP4F2CYP4A11HPGDSGPR119SCN9A | |
| SCHEMBL16757836 | 0.90 | GPR119 (0.42) | CYP4F2CYP4A11HPGDSGPR119 | |
| SCHEMBL16758005 | 0.87 | WDR5 (0.37) | HPGDS | |
| SCHEMBL16757762 | 0.87 | GPR119 (0.35) | CYP4F2CYP4A11GPR119SCN9A | |
| SCHEMBL16757750 | 0.86 | GPR119 (0.46) | CYP4F2CYP4A11HPGDSGPR119SCN9A | |
| SCHEMBL16757851 | 0.85 | CYP4F2 (0.36) | CYP4F2CYP4A11HPGDSGPR119SCN9A | |
| SCHEMBL16758261 | 0.83 | GPR119 (0.38) | CYP4F2CYP4A11HPGDSGPR119 | |
| SCHEMBL16757862 | 0.82 | GPR119 (0.43) | CYP4F2CYP4A11HPGDSGPR119 | |
| SCHEMBL16757902 | 0.82 | SSTR5 (0.43) | CYP4F2CYP4A11HPGDSGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074384-A1 | AMIDE DERIVATIVES FOR GPR119 AGONIST | Chong Kun Dang Pharmaceutical Corp. (KR) | 2016-10-05 | — | — | EP | claimed |
| WO-2015080446-A1 | AMIDE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2015-06-04 | — | — | WO | claimed |
| EP-3074384-A1 | AMIDE DERIVATIVES FOR GPR119 AGONIST | Chong Kun Dang Pharmaceutical Corp. (KR) | 2016-10-05 | — | — | EP | disclosed |
| WO-2015080446-A1 | AMIDE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2015-06-04 | — | — | WO | disclosed |