Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.40 |
| ▸ | FEN1 | P39748 | 2/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 6/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 6/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16758262 | 1.00 | GPR119 (0.42) | GPR119ALOX5APFEN1CYP4F2CYP4A11 | |
| SCHEMBL15540005 | 0.94 | GPR119 (0.43) | GPR119ALOX5APFEN1CYP4F2CYP4A11 | |
| SCHEMBL15540003 | 0.94 | GPR119 (0.43) | GPR119ALOX5APFEN1CYP4F2CYP4A11 | |
| SCHEMBL21043506 | 0.92 | ALOX5AP (0.41) | GPR119ALOX5APFEN1CYP4F2CYP4A11 | |
| SCHEMBL18849087 | 0.92 | ALOX5AP (0.41) | GPR119ALOX5APFEN1CYP4F2CYP4A11 | |
| SCHEMBL15539561 | 0.89 | ALOX5AP (0.42) | GPR119ALOX5APFEN1CYP4F2CYP4A11 | |
| SCHEMBL15539563 | 0.89 | ALOX5AP (0.42) | GPR119ALOX5APFEN1CYP4F2CYP4A11 | |
| SCHEMBL18849001 | 0.88 | GPR119 (0.53) | GPR119CYP4F2CYP4A11HRH3 | |
| SCHEMBL16768907 | 0.87 | GPR119 (0.42) | GPR119CYP4F2CYP4A11 | |
| SCHEMBL16757782 | 0.86 | GPR119 (0.43) | GPR119CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9776987-B2 | Amide derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2017-10-03 | — | — | US | disclosed |
| US-20170129875-A1 | AMIDE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2017-05-11 | — | — | US | disclosed |
| EP-3074384-A1 | AMIDE DERIVATIVES FOR GPR119 AGONIST | Chong Kun Dang Pharmaceutical Corp. (KR) | 2016-10-05 | — | — | EP | disclosed |
| WO-2015080446-A1 | AMIDE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2015-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170129875-A1 | AMIDE DERIVATIVES FOR GPR119 AGONIST | GPR119, FFAR2, GLP1R | GPR119 1/4885ALOX5AP 1031/4885FEN1 4883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.