Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 19/20 | 0.77 |
| ▸ | BRD2 | P25440 | 17/20 | 0.77 |
| ▸ | BRD3 | Q15059 | 17/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14757093 | 0.83 | BRD4 (0.72) | BRD4BRD2BRD3 | |
| SCHEMBL14757248 | 0.80 | BRD4 (0.74) | BRD4BRD2BRD3 | |
| SCHEMBL15968112 | 0.78 | BRD4 (0.81) | BRD4BRD2BRD3 | |
| SCHEMBL15980799 | 0.78 | BRD4 (0.76) | BRD4BRD2BRD3 | |
| SCHEMBL14757312 | 0.77 | BRD4 (0.73) | BRD4BRD2BRD3 | |
| SCHEMBL16758412 | 0.76 | BRD4 (0.69) | BRD4BRD2BRD3 | |
| SCHEMBL28607385 | 0.76 | BRD4 (0.69) | BRD4BRD2BRD3 | |
| SCHEMBL14740758 | 0.75 | BRD4 (1.00) | BRD4BRD2BRD3 | |
| SCHEMBL14756139 | 0.75 | BRD4 (0.71) | BRD4BRD2BRD3 | |
| SCHEMBL16771417 | 0.74 | BRD4 (1.00) | BRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015081280-A1 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION | COFERON, INC. (US) | 2015-06-04 | — | — | WO | disclosed |
| WO-2015081280-A1 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION | COFERON, INC. (US) | 2015-06-04 | — | — | WO | disclosed |