Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.69 |
| ▸ | BRD2 | P25440 | 20/20 | 0.69 |
| ▸ | BRD3 | Q15059 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14740769 | 0.83 | BRD4 (0.74) | BRD4BRD2BRD3 | |
| SCHEMBL16771417 | 0.80 | BRD4 (1.00) | BRD4BRD2BRD3 | |
| SCHEMBL8387039 | 0.76 | BRD4 (0.55) | BRD4BRD2BRD3 | |
| SCHEMBL16758351 | 0.76 | BRD4 (0.77) | BRD4BRD2BRD3 | |
| SCHEMBL8326046 | 0.76 | ERN1 (0.72) | BRD4BRD2BRD3 | |
| SCHEMBL23997128 | 0.74 | BRD4 (0.53) | BRD4BRD2BRD3 | |
| SCHEMBL15980908 | 0.73 | BRD4 (0.76) | BRD4BRD2BRD3 | |
| SCHEMBL15653363 | 0.73 | ALDH1A1 (0.56) | BRD4BRD2BRD3 | |
| SCHEMBL21609042 | 0.73 | MAPT (0.49) | — | |
| SCHEMBL14740758 | 0.72 | BRD4 (1.00) | BRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912584-B | BRD4 protein inhibitor with anti-tumor activity and preparation method and application thereof | 中国药科大学 | 2021-08-13 | — | — | CN | disclosed |