Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 19/20 | 0.56 |
| ▸ | CCR3 | P51677 | 19/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.56 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16770993 | 0.95 | HRH1 (0.61) | HRH1CCR3KCNH2SCN9A | |
| Trifluoroacetic Acid SCHEMBL28336567 | 0.91 | HRH1 (0.45) | HRH1CCR3KCNH2SCN9A | |
| SCHEMBL16771133 | 0.90 | HRH1 (0.50) | HRH1CCR3KCNH2SCN9A | |
| Trifluoroacetic Acid SCHEMBL16759040 | 0.89 | SSTR5 (0.47) | HRH1CCR3KCNH2SCN9A | |
| Hydrochloric Acid SCHEMBL17062149 | 0.89 | HRH1 (0.49) | HRH1CCR3KCNH2SCN9A | |
| Trifluoroacetic Acid SCHEMBL16759039 | 0.88 | SCN9A (0.56) | HRH1CCR3KCNH2SCN9A | |
| SCHEMBL28338328 | 0.88 | HRH1 (0.49) | HRH1CCR3KCNH2SCN9A | |
| Trifluoroacetic Acid SCHEMBL28338837 | 0.88 | ADRB2 (0.47) | HRH1CCR3KCNH2SCN9A | |
| Trifluoroacetic Acid SCHEMBL16759198 | 0.87 | SCN9A (0.59) | HRH1CCR3KCNH2SCN9A | |
| SCHEMBL16770800 | 0.87 | SCN9A (0.53) | HRH1CCR3KCNH2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793238-B | Substituted benzamides and methods of use thereof | 基因泰克公司 | 2019-12-24 | — | — | CN | disclosed |
| EP-3074377-A1 | SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | Genentech, Inc. (US) | 2016-10-05 | — | — | EP | disclosed |
| WO-2015078374-A1 | SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2015-06-04 | — | — | WO | disclosed |