Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 17/20 | 0.49 |
| ▸ | CCR3 | P51677 | 17/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN4A | P35499 | 1/20 | 0.40 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28336566 | 0.91 | SCN9A (0.43) | HRH1CCR3KCNH2SCN9ASCN1A | |
| Trifluoroacetic Acid SCHEMBL16759246 | 0.88 | HRH1 (0.56) | HRH1CCR3KCNH2SCN9A | |
| SCHEMBL16758975 | 0.87 | CCR3 (0.49) | HRH1CCR3KCNH2SCN9ASCN1A | |
| SCHEMBL16770993 | 0.87 | HRH1 (0.61) | HRH1CCR3KCNH2SCN9A | |
| SCHEMBL16770800 | 0.86 | SCN9A (0.53) | HRH1CCR3KCNH2SCN9A | |
| SCHEMBL21825328 | 0.86 | FFAR1 (0.46) | HRH1CCR3KCNH2SCN9ASCN1A | |
| SCHEMBL28335968 | 0.86 | SCN9A (0.40) | HRH1CCR3SCN9ASCN1ASCN4A | |
| Trifluoroacetic Acid SCHEMBL16759039 | 0.82 | SCN9A (0.56) | HRH1CCR3KCNH2SCN9ASCN1A | |
| SCHEMBL17061977 | 0.82 | MGLL (0.41) | SCN9ASCN1ASCN4ASCN7ASCN5A | |
| Trifluoroacetic Acid SCHEMBL16759198 | 0.81 | SCN9A (0.59) | HRH1CCR3KCNH2SCN9ASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793238-B | Substituted benzamides and methods of use thereof | 基因泰克公司 | 2019-12-24 | — | — | CN | disclosed |