SCHEMBL16760587

SCHEMBL16760587

O=C1NC(=O)c2c1csc2-c1cccs1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.43
SLC6A11 P48066 1/20 0.41
MAOB P27338 1/20 0.41
CHEK1 O14757 2/20 0.40
WEE1 P30291 1/20 0.40
LTK P29376 1/20 0.40
CDK5 Q00535 1/20 0.40
MST1R Q04912 1/20 0.40
DYRK1A Q13627 1/20 0.40
CLK4 Q9HAZ1 1/20 0.40
GSK3B P49841 3/20 0.38
PRKCA P17252 1/20 0.38
ALDH1A1 P00352 6/20 0.38
HPGD P15428 3/20 0.38
TYMP P19971 1/20 0.37
KDM4E B2RXH2 5/20 0.36
MAPT P10636 5/20 0.36
HSD17B10 Q99714 3/20 0.36
GAA P10253 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29177041 0.79 SLC6A11 (0.41) MAOASLC6A11MAOBCHEK1WEE1
SCHEMBL606360 0.76 LTK (0.53) MAOASLC6A11MAOBCHEK1WEE1
SCHEMBL28680527 0.75 CHEK1 (0.47) MAOASLC6A11MAOBCHEK1WEE1
Phthalimide SCHEMBL16027142 0.74 GSK3B (0.62) MAOASLC6A11MAOBLTKCDK5
SCHEMBL19143756 0.73 CHEK1 (0.52) MAOASLC6A11MAOBCHEK1WEE1
SCHEMBL19742067 0.72 KDM4E (0.39) LTKCDK5MST1RDYRK1ACLK4
SCHEMBL20414677 0.70 TYMP (0.44) MAOASLC6A11MAOBCHEK1WEE1
SCHEMBL16369828 0.70 GSK3B (0.56) MAOASLC6A11MAOBCHEK1WEE1
SCHEMBL18170821 0.70 CHEK1 (0.46) MAOASLC6A11MAOBCHEK1WEE1
SCHEMBL1487707 0.69 ALOX5 (0.39) ALDH1A1HPGDKDM4EMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3333920-B1 PHOTOVOLTAIC CELL PROVIDED WITH A COMPOSITE N-LAYER COMMISSARIAT ENERGIE ATOMIQUE (FR) 2023-01-25 EP claimed
EP-3333920-A1 PHOTOVOLTAIC CELL PROVIDED WITH A COMPOSITE N-LAYER Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2018-06-13 EP claimed
EP-3075015-A1 ORGANIC ELECTRONIC DEVICES Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) 2016-10-05 EP claimed
WO-2015079380-A1 ORGANIC ELECTRONIC DEVICES COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-06-04 WO claimed
EP-3333920-B1 PHOTOVOLTAIC CELL PROVIDED WITH A COMPOSITE N-LAYER COMMISSARIAT ENERGIE ATOMIQUE (FR) 2023-01-25 EP disclosed
EP-3333920-A1 PHOTOVOLTAIC CELL PROVIDED WITH A COMPOSITE N-LAYER Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2018-06-13 EP disclosed
EP-3075015-A1 ORGANIC ELECTRONIC DEVICES Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) 2016-10-05 EP disclosed
WO-2015079380-A1 ORGANIC ELECTRONIC DEVICES COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-06-04 WO disclosed