Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 11/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL1014927 | 0.93 | GAA (0.35) | GAAMAPTKMT2ACYP2C19HIF1A | |
| Ethylenediamine SCHEMBL9223549 | 0.93 | KIF11 (0.42) | KIF11TAAR1SMN1; SMN2 | |
| 1,4-Butanediol SCHEMBL7069258 | 0.88 | GAA (0.32) | GAAMAPTCYP2C19HIF1A | |
| SCHEMBL1073351 | 0.84 | KIF11 (0.44) | KIF11TAAR1CYP2C19 | |
| SCHEMBL16895246 | 0.84 | CNR2 (0.33) | GAAMAPTCYP2C19HIF1A | |
| SCHEMBL1149592 | 0.83 | KCNN4 (0.36) | TAAR1MAPTKMT2ACYP2C19HIF1A | |
| SCHEMBL15413 | 0.83 | KCNN4 (0.36) | TAAR1MAPTKMT2ACYP2C19HIF1A | |
| Water SCHEMBL10334361 | 0.81 | KCNN4 (0.35) | MAPTKMT2ACYP2C19HIF1A | |
| Water SCHEMBL2069627 | 0.81 | KCNN4 (0.35) | MAPTKMT2ACYP2C19HIF1A | |
| SCHEMBL8578358 | 0.81 | KCNN4 (0.35) | MAPTKMT2ACYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9778402-B2 | Light reflective film and light reflector produced using the same | Konica Minolta, Inc. (JP) | 2017-10-03 | — | — | US | disclosed |
| US-20150219810-A1 | LIGHT REFLECTIVE FILM AND LIGHT REFLECTOR PRODUCED USING THE SAME | Konica Minolta, Inc. (JP) | 2015-08-06 | — | — | US | disclosed |
| EP-2881769-A1 | LIGHT-REFLECTIVE FILM, AND LIGHT REFLECTOR PRODUCED USING SAME | Konica Minolta, Inc. (JP) | 2015-06-10 | — | — | EP | disclosed |