Ethylene Glycol

Ethylene Glycol

SCHEMBL1014927

O=C=NC(N=C=O)(c1ccccc1)c1ccccc1.OCCO

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.35
CYP2C19 P33261 2/20 0.34
HIF1A Q16665 1/20 0.34
CYP1A2 P05177 2/20 0.33
TSHR P16473 2/20 0.32
PTPN1 P18031 1/20 0.32
CYP2C9 P11712 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CA5A P35218 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
KMT2A Q03164 3/20 0.32
MEN1 O00255 2/20 0.32
ALDH1A1 P00352 3/20 0.32
MAPT P10636 1/20 0.31
KCNN4 O15554 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Butanediol SCHEMBL7069258 0.94 GAA (0.32) GAACYP2C19HIF1ACYP1A2TSHR
Ethylenediamine SCHEMBL16760973 0.93 KIF11 (0.38) GAACYP2C19HIF1AKMT2AMAPT
SCHEMBL16895246 0.91 CNR2 (0.33) GAACYP2C19HIF1ACYP1A2TSHR
SCHEMBL1149592 0.89 KCNN4 (0.36) CYP2C19HIF1ACYP1A2TSHRPTPN1
SCHEMBL15413 0.89 KCNN4 (0.36) CYP2C19HIF1ACYP1A2TSHRPTPN1
Water SCHEMBL10334361 0.87 KCNN4 (0.35) CYP2C19HIF1ACYP1A2TSHRPTPN1
SCHEMBL2476985 0.87 KCNN4 (0.35) CYP2C19HIF1ACYP1A2TSHRPTPN1
Water SCHEMBL2069627 0.87 KCNN4 (0.35) CYP2C19HIF1ACYP1A2TSHRPTPN1
SCHEMBL8578358 0.87 KCNN4 (0.35) CYP2C19HIF1ACYP1A2TSHRPTPN1
SCHEMBL19128956 0.87 KCNN4 (0.35) CYP2C19HIF1ACYP1A2TSHRPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111944492-A Preparation method of graphene nano composite phase change material with cold accumulation characteristic 哈尔滨商业大学 2020-11-17 CN claimed
CN-111944492-A Preparation method of graphene nano composite phase change material with cold accumulation characteristic 哈尔滨商业大学 2020-11-17 CN disclosed
WO-2015187632-A1 POLYMERIC FILMS COMPRISING ANTIMICROBIAL AGENTS AVERY DENNISON CORPORATION (US) 2015-12-10 WO disclosed
EP-2055327-B1 Antimicrobial lubricious coating COVIDIEN LP (US) 2013-12-11 EP disclosed
EP-2259765-B1 COSMETIC METHOD FOR SMOOTHING WRINKLES AND FINE LINES USING AN INTERPOLYMER CHANEL PARFUMS BEAUTE (FR) 2012-08-15 EP disclosed
US-20110014150-A1 COSMETIC METHOD FOR SMOOTHING WRINKLES AND FINE LINES CHANEL PARFUMS BEAUTE (FR) 2011-01-20 US disclosed
EP-2259765-A1 COSMETIC METHOD FOR SMOOTHING WRINKLES AND FINE LINES USING AN INTERPOLYMER Chanel Parfums Beauté (FR) 2010-12-15 EP disclosed
US-7820734-B2 Antimicrobial lubricious coating TYCO HEALTHCARE GROUP LP (US) 2010-10-26 US disclosed
WO-2009124976-A1 COSMETIC METHOD FOR SMOOTHING WRINKLES AND FINE LINES USING AN INTERPOLYMER CHANEL PARFUMS BEAUTE (FR) 2009-10-15 WO disclosed
EP-2055327-A1 Antimicrobial lubricious coating Tyco Healthcare Group LP (US) 2009-05-06 EP disclosed
US-6054504-A Biostatic coatings for the reduction and prevention of bacterial adhesion HYDROMER, INC. (US) 2000-04-25 US disclosed
EP-0520160-A1 Process for antimicrobial treatment of polyurethane BOC HEALTH CARE, Inc. (US) 1992-12-30 EP disclosed
US-4875287-A Shaving articles lubricious when wet and compositions therefor HYDROMER, INC. (US) 1989-10-24 US disclosed
US-4769013-A Bio-effecting medical material and device HYDROMER, INC. (US) 1988-09-06 US disclosed
US-4642267-A Hydrophilic polymer blend HYDROMER, INC. (US) 1987-02-10 US disclosed
US-4576156-A Prophylactic device and method ORTHO PHARMACEUTICAL CORPORATION (US) 1986-03-18 US disclosed
US-4568717-A REACTING PRODUCT FO PET AND AN OXYALKYLENE GLYCOL WITH A POLYISOCYANATE TEXACO, INC. (US) 1986-02-04 US disclosed
US-4540768-A POLYISOCYANATE, AMINE CHAIN EXTENDER, REACTION INJECTION MOLDING TEXACO INC. (US) 1985-09-10 US disclosed
US-4119094-A Coated substrate having a low coefficient of friction hydrophilic coating and a method of making the same BIOSEARCH MEDICAL PRODUCTS INC. (US) 1978-10-10 US disclosed
US-4100309-A Coated substrate having a low coefficient of friction hydrophilic coating and a method of making the same BIOSEARCH MEDICAL PRODUCTS, INC. (US) 1978-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110014150-A1 COSMETIC METHOD FOR SMOOTHING WRINKLES AND FINE LINES CUTA, SPOP, VCL GAA 2578/4885CYP2C19 1570/4885HIF1A 4652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.