Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5035941 | 0.72 | MEN1 (0.40) | MAPK1KMT2AMEN1POLBPSMB8 | |
| SCHEMBL1665299 | 0.71 | NPC1 (0.56) | APPNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL31310542 | 0.71 | NPC1 (0.56) | APPNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL16763492 | 0.71 | PTPN1 (0.48) | APPNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL28332329 | 0.70 | KMT2A (0.61) | NPC1RAB9AMAPK1MAPTKMT2A | |
| SCHEMBL6173418 | 0.70 | RAB9A (0.68) | APPNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL1181273 | 0.68 | APP (1.00) | APPNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL7089083 | 0.68 | NPC1 (0.62) | NPC1RAB9AMAPK1MAPTKMT2A | |
| SCHEMBL30620465 | 0.68 | MEN1 (0.73) | NPC1MAPK1KMT2AMEN1POLB | |
| SCHEMBL1224829 | 0.68 | MEN1 (0.73) | NPC1MAPK1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611281-B2 | BODIPY derivatives and methods of synthesis and use thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2017-04-04 | — | — | US | disclosed |
| US-20150158888-A1 | BODIPY Derivatives and Methods of Synthesis and Use Thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2015-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150158888-A1 | BODIPY Derivatives and Methods of Synthesis and Use Thereof | FDPS, FDFT1, BCR | APP 1766/4885NPC1 29/4885RAB9A 2603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.