Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | DAO | P14920 | 1/20 | 0.67 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.67 |
| ▸ | CES1 | P23141 | 4/20 | 0.56 |
| ▸ | CES2 | O00748 | 3/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL10791101 | 0.85 | TSHR (0.82) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL976149 | 0.82 | TSHR (1.00) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL407365 | 0.82 | TSHR (1.00) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL11602198 | 0.82 | TSHR (1.00) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL7719037 | 0.82 | TSHR (1.00) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL3966600 | 0.82 | TSHR (1.00) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL137419 | 0.82 | TSHR (1.00) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL149318 | 0.82 | TSHR (1.00) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL975929 | 0.82 | TSHR (1.00) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL1378 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906707-B1 | METHOD OF MAKING POLYHYDROXYALKANOATE COPOLYMERS (3HB-CO-4HB) | CJ CHEILJEDANG CORP (KR) | 2019-07-24 | — | — | EP | disclosed |
| US-10323261-B2 | Polyhydroxyalkanoate copolymer compositions and methods of making the same | CJ CHEILJEDANG CORPORATION (KR) | 2019-06-18 | — | — | US | disclosed |
| US-20180057848-A1 | POLYHYDROXYALKANOATE COPOLYMER COMPOSITIONS AND METHODS OF MAKING THE SAME | CJ CHEILJEDANG CORPORATION (KR) | 2018-03-01 | — | — | US | disclosed |
| US-20150240273-A1 | POLYHYDROXYALKANOATE COPOLYMER COMPOSITIONS AND METHODS OF MAKING THE SAME | METABOLIX, INC. (US) | 2015-08-27 | — | — | US | disclosed |
| EP-2906707-A1 | POLYHYDROXYALKANOATE COPOLYMER COMPOSITIONS AND METHODS OF MAKING THE SAME | Metabolix, Inc. (US) | 2015-08-19 | — | — | EP | disclosed |
| US-20150159184-A1 | Genetically Engineered Microorganisms for the Production of Poly-4-Hydroxybutyrate | METABOLIX, INC. | 2015-06-11 | — | — | US | disclosed |