Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL11602198 | 1.00 | TSHR (1.00) | — | |
| Benzoic Acid SCHEMBL1095403 | 1.00 | TSHR (1.00) | — | |
| Benzoic Acid SCHEMBL4591761 | 1.00 | TSHR (1.00) | — | |
| Benzoic Acid SCHEMBL407365 | 1.00 | TSHR (1.00) | — | |
| Benzoic Acid SCHEMBL3966600 | 1.00 | TSHR (1.00) | — | |
| Benzoic Acid SCHEMBL160564 | 1.00 | TSHR (1.00) | — | |
| Benzoic Acid SCHEMBL2458489 | 1.00 | TSHR (1.00) | — | |
| Benzoic Acid SCHEMBL9751726 | 1.00 | TSHR (1.00) | — | |
| Benzoic Acid SCHEMBL976149 | 1.00 | TSHR (1.00) | — | |
| Benzoic Acid SCHEMBL7719037 | 1.00 | TSHR (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 1008153 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413925-B1 | — | — | None | — | — | US | claimed |
| US-6436477-B1 | — | — | None | — | — | US | claimed |
| US-6410805-B1 | — | — | None | — | — | US | claimed |
| US-9976051-B2 | Self healing polymer compositions | PETROLIAM NASIONAL BERHAD (PETRONAS) (MY) | 2018-05-22 | — | — | US | claimed |
| US-9974693-B2 | Devices, systems, and methods for instillation of foamed fluid with negative pressure wound therapy | KCI LICENSING, INC. (US) | 2018-05-22 | — | — | US | claimed |
| US-9975847-B2 | Amino acid derivatives and their uses | JOHNSON & JOHNSON CONSUMER INC. (US) | 2018-05-22 | — | — | US | claimed |
| US-9975967-B2 | Cellulose ester optical films | EASTMAN CHEMICAL COMPANY (US) | 2018-05-22 | — | — | US | claimed |
| US-9974784-B2 | Inhibitors of activin-like receptor kinases | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2018-05-22 | — | — | US | claimed |
| US-9975915-B1 | Crystalline forms of nicotinoyl ribosides, modified derivatives thereof, and phosphorylated analogs thereof, and methods of preparation thereof | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2018-05-22 | — | — | US | claimed |
| US-20180134742-A1 | CRYSTALLINE FORMS OF NICOTINOYL RIBOSIDES, MODIFIED DERIVATIVES THEREOF, AND PHOSPHORYLATED ANALOGS THEREOF, AND METHODS OF PREPARATION THEREOF | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2018-05-17 | — | — | US | claimed |
| US-3941818-A | 1:1 Zinc methionine complexes | ZINPRO CORPORATION (US) | 1976-03-02 | — | — | US | claimed |
| US-3939146-A | VIRICIDE | STRATEGIC MEDICAL RESEARCH CORPORATION (US) | 1976-02-17 | — | — | US | claimed |
| US-3939145-A | VIRICIDE | STRATEGIC MEDICAL RESEARCH CORPORATION (US) | 1976-02-17 | — | — | US | claimed |
| US-3937808-A | SUN TANNING AND HARI PROTECTING ACID SALTS OF AMINOMETHYL-O-HYDROXYPHENONES COMPOSITIONS | GAF CORPORATION (US) | 1976-02-10 | — | — | US | claimed |
| US-3937809-A | ADDITION COMPOUND OF A NUCLEOTIDE AND AN AMINO ACID AND THE USE THEREOF IN PROTECTION AGAINST ACTINIC RADIATION | KOLMAR LABORATORIES, INC. (US) | 1976-02-10 | — | — | US | claimed |
| US-3936491-A | Adamantylene compounds | U.S. PHILIPS CORPORATION (US) | 1976-02-03 | — | — | US | claimed |
| US-3933797-A | 6-[α-(ω-QUANIDINOALKANOYLAMIDO)ACYLAMIDO]PENICILLANIC ACIDS | PFIZER INC. (US) | 1976-01-20 | — | — | US | claimed |
| US-3933799-A | HORMONES | GLAXO LABORATORIES LIMITED (EN) | 1976-01-20 | — | — | US | claimed |
| US-3930866-A | MAGENTA | FUJI PHOTO FILM CO., LTD. (JA) | 1976-01-06 | — | — | US | claimed |
| US-3931145-A | POLYESTER | GAF CORPORATION (US) | 1976-01-06 | — | — | US | claimed |