SCHEMBL1676646

SCHEMBL1676646

FC(F)(F)c1ccccc1Oc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.53
PTGS2 P35354 1/20 0.53
TSHR P16473 1/20 0.46
LPAR1 Q92633 1/20 0.45
LPAR5 Q9H1C0 1/20 0.45
RIPK1 Q13546 1/20 0.44
FFAR1 O14842 1/20 0.44
LMNA P02545 1/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 1/20 0.44
RXRA P19793 1/20 0.42
RXRB P28702 1/20 0.42
RXRG P48443 1/20 0.42
PPARG P37231 1/20 0.42
AR P10275 5/20 0.42
HRH1 P35367 1/20 0.41
CTNNB1 P35222 1/20 0.41
MAOB P27338 1/20 0.41
MRGPRX1 Q96LB2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11521654 0.93 LTA4H (0.58) LTA4HPTGS2LPAR1LPAR5FFAR1
SCHEMBL1685381 0.86 LTA4H (0.46) LTA4HPTGS2RXRARXRBRXRG
SCHEMBL14677727 0.86 LTA4H (0.52) LTA4HPTGS2TSHRLPAR1LPAR5
SCHEMBL919536 0.84 LTA4H (0.48) LTA4HPTGS2LPAR1LPAR5FFAR1
SCHEMBL4308678 0.84 LTA4H (0.51) LTA4HPTGS2LPAR1LPAR5FFAR1
SCHEMBL476252 0.84 NCOA1 (0.51) LTA4HPTGS2TSHRLPAR1LPAR5
SCHEMBL5536466 0.84 LTA4H (0.51) LTA4HPTGS2LPAR1LPAR5FFAR1
SCHEMBL3967756 0.84 LTA4H (0.51) LTA4HPTGS2LPAR1LPAR5FFAR1
SCHEMBL2314095 0.84 LTA4H (0.51) LTA4HPTGS2LPAR1LPAR5FFAR1
SCHEMBL29553142 0.84 NCOA1 (0.51) LTA4HPTGS2TSHRLPAR1LPAR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113968970-A Polyimide film with low thermal expansion coefficient, and preparation method and application thereof 浙江中科玖源新材料有限公司 2022-01-25 CN claimed
CN-113943419-A High-temperature-resistant low-CTE polyimide film and preparation method and application thereof 浙江中科玖源新材料有限公司 2022-01-18 CN claimed
JP-2178255-A None JP disclosed
WO-2024063048-A1 LAMINATE, TOUCH PANEL MEMBER, AND DISPLAY DEVICE 大日本印刷株式会社 2024-03-28 WO disclosed
WO-2022210725-A1 LAMINATE FOR DISPLAY DEVICE AND DISPLAY DEVICE 大日本印刷株式会社 2022-10-06 WO disclosed
WO-2022191319-A1 MULTILAYER BODY FOR DISPLAY DEVICES, AND DISPLAY DEVICE 大日本印刷株式会社 2022-09-15 WO disclosed
CN-114479076-A Low-dielectric polyimide film and preparation method and application thereof 浙江中科玖源新材料有限公司 2022-05-13 CN disclosed
CN-113968970-A Polyimide film with low thermal expansion coefficient, and preparation method and application thereof 浙江中科玖源新材料有限公司 2022-01-25 CN disclosed
CN-113943419-A High-temperature-resistant low-CTE polyimide film and preparation method and application thereof 浙江中科玖源新材料有限公司 2022-01-18 CN disclosed
US-20110092553-A1 Substituted Azole Derivatives, Compositions, and Methods of Use TRANSTECH PHARMA, INC. (US) 2011-04-21 US disclosed
EP-1730118-A1 SUBSTITUTED AZOLE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE Transtech Pharma, Inc. (US) 2006-12-13 EP disclosed
EP-0219179-B1 THE PREPARATION OF SUBSTITUTED 3'-HALOPIPHENYLETHERS ROHM AND HAAS COMPANY (US) 1990-11-07 EP disclosed
JP-H02178255-A NOVEL HALOGENATED TRIFLUOROMETHYLBENZENE OCCIDENTAL CHEM CORP 1990-07-11 JP disclosed
EP-0206951-B1 PROCESS FOR THE PERFLUOROALKYLATION OF AROMATIC DERIVATIVES RHONE-POULENC CHIMIE (FR) 1990-03-21 EP disclosed
EP-0298803-A1 Process for the perhaloalkylation of aromatic derivatives RHONE-POULENC CHIMIE (FR) 1989-01-11 EP disclosed
US-4731450-A Process for perfluoroalkylation of aromatic derivatives RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1988-03-15 US disclosed
EP-0206951-A2 Process for the perfluoroalkylation of aromatic derivatives RHONE-POULENC CHIMIE (FR) 1986-12-30 EP disclosed
US-4450308-A Process for the preparation of trifluoromethylphenyl oxyphenyl ether compounds BAYER AKTIENGESELLSCHAFT (DE) 1984-05-22 US disclosed
EP-0033885-B1 PROCESS FOR THE PREPARATION OF (2-CHLORO-4-TRIFLUORMETHYL-PHENYL)-(3-METHOXY-PHENYL)-ETHER BAYER AG (DE) 1984-03-21 EP disclosed
EP-0033885-A1 Process for the preparation of (2-chloro-4-trifluormethyl-phenyl)-(3-methoxy-phenyl)-ether BAYER AG (DE) 1981-08-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110092553-A1 Substituted Azole Derivatives, Compositions, and Methods of Use PTPRO, PTPN5, PTPRE LTA4H 1580/4885PTGS2 1321/4885TSHR 3409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.