SCHEMBL1676679

SCHEMBL1676679

O=C1C=C(N2CC2)C(=O)C=C1N1CC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.52
MAPT P10636 5/20 0.48
HTT P42858 2/20 0.48
KMT2A Q03164 2/20 0.48
LMNA P02545 1/20 0.48
TP53 P04637 1/20 0.43
STAT3 P40763 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
APAF1 O14727 2/20 0.42
TDP2 O95551 2/20 0.42
NSD2 O96028 2/20 0.42
HKDC1 Q2TB90 2/20 0.42
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
GALK1 P51570 1/20 0.39
BLM P54132 1/20 0.39
ATM Q13315 1/20 0.39
NOD2 Q9HC29 1/20 0.39
ATG4B Q9Y4P1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8958544 0.88 DNMT1 (0.52) DNMT1MAPTHTTKMT2ALMNA
SCHEMBL8843222 0.78 NSD2 (0.48) DNMT1MAPTKMT2ANSD2MEN1
SCHEMBL1420707 0.78 DNMT1 (0.41) DNMT1MAPTHTTKMT2ALMNA
SCHEMBL8958416 0.76 MAPT (0.46) DNMT1MAPTHTTKMT2ALMNA
Triaziquone SCHEMBL8303 0.76 DNMT1 (0.48) DNMT1MAPTHTTKMT2ALMNA
Triaziquone SCHEMBL6000230 0.75 DNMT1 (0.47) DNMT1MAPTHTTKMT2ALMNA
Triaziquone SCHEMBL5054475 0.75 DNMT1 (0.47) DNMT1MAPTHTTKMT2ALMNA
Triaziquone SCHEMBL8482641 0.75 DNMT1 (0.47) DNMT1MAPTHTTKMT2ALMNA
Triaziquone SCHEMBL8993238 0.75 DNMT1 (0.47) DNMT1MAPTHTTKMT2ALMNA
Triaziquone SCHEMBL7738777 0.75 DNMT1 (0.47) DNMT1MAPTHTTKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12297500-B2 Transcriptomic index for characterizing the cellular repair response after soft tissue injury in diarthrodial joints RUSH UNIVERSITY MEDICAL CENTER (US) 2025-05-13 US claimed
CN-114333292-B Traffic restoration method based on trajectory reconstruction technology 上海电科智能系统股份有限公司 2022-11-18 CN claimed
EP-2900236-B1 TREATMENT OF WOLFRAM SYNDROME-RELATED NEURODEGENERATION UNIV BIRMINGHAM (GB) 2019-01-16 EP claimed
US-20090123447-A1 COMPOSITIONS AND METHODS TO INHIBIT RNA VIRAL REPRODUCTION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2009-05-14 US claimed
EP-1017852-A1 OBTAINING NUCLEIC ACID SEQUENCES The Victoria University of Manchester (GB) 2000-07-12 EP claimed
US-6066457-A ANCHORING SINGLE STRANDED CDNA PRODUCED FROM STARTING MATERIAL AND USING RANDOM PRIMING AND SEPARATION STEPS TO PRODUCE SHORTER RANDOM SIZE DNA FOR UNIFORM POLYMERASE CHAIN REACTION AMPLIFICATION USEFUL IN SUBTRACTIVE HYBRIDIZATION CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 2000-05-23 US claimed
WO-1999018236-A1 OBTAINING NUCLEIC ACID SEQUENCES THE VICTORIA UNIVERSITY OF MANCHESTER (GB) 1999-04-15 WO claimed
EP-0864001-A1 GLOBAL AMPLIFICATION OF NUCLEIC ACIDS CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 1998-09-16 EP claimed
WO-1998008973-A1 GLOBAL AMPLIFICATION OF NUCLEIC ACIDS CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 1998-03-05 WO claimed
US-5591575-A Subtraction hybridization employing aziridinylbenoquinone cross-linking agents AMERSHAM INTERNATIONAL PLC (GB) 1997-01-07 US claimed
US-5589339-A Subtraction hybridization AMERSHAM INTERNATIONAL PLC (GB) 1996-12-31 US claimed
US-4238484-A O,O-DIALKYL-O-/3-BENZOTHIENGLYOXYLONITRILE OXIMO/PHOSPHATE ABBOTT LABORATORIES (US) 1980-12-09 US claimed
WO-2026107259-A1 BIOMARKERS FOR CANCER DETECTION NEXOSOME ONCOLOGY LLC (US) 2026-05-21 WO disclosed
EP-4219735-B1 METHOD AND APPARATUS FOR ANALYTE DETECTION USING AN ELECTROCHEMICAL BIOSENSOR ABBOTT DIABETES CARE (US) 2026-04-01 EP disclosed
EP-3496763-B1 PYRROLOBENZODIAZEPINE PRODRUGS AND ANTIBODY CONJUGATES THEREOF GENENTECH INC (US) 2026-04-01 EP disclosed
US-20260083672-A1 FORMULATIONS AND DOSAGE AMOUNTS FOR ADMINISTERING AN ANTI-DPP3 ANTIBODY OR FRAGMENT THEREOF TO HUMANS 4TEEN4 Pharmaceuticals GmbH (DE) 2026-03-26 US disclosed
US-4704384-A BRAIN TUMORS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1987-11-03 US disclosed
US-4238484-A O,O-DIALKYL-O-/3-BENZOTHIENGLYOXYLONITRILE OXIMO/PHOSPHATE ABBOTT LABORATORIES (US) 1980-12-09 US disclosed
US-4233215-A Aziridinyl quinone antitumor agents UNITED STATES OF AMERICA (US) 1980-11-11 US disclosed
US-4146622-A AZIRIDINYL QUINONE ANTI-TRANSPLANTED TUMOR AGENTS THE GOVERNMENT OF THE UNITED STATES (US) 1979-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083672-A1 FORMULATIONS AND DOSAGE AMOUNTS FOR ADMINISTERING AN ANTI-DPP3 ANTIBODY OR FRAGMENT THEREOF TO HUMANS DPP3, DPP4, TREH DNMT1 3993/4885MAPT 824/4885HTT 3417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.