Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 3/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 7/20 | 0.32 |
| ▸ | FEN1 | P39748 | 7/20 | 0.32 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26802865 | 1.00 | OPRL1 (0.34) | OPRL1NOTUMHPGDALOX5APFEN1 | |
| SCHEMBL26802888 | 1.00 | OPRL1 (0.34) | OPRL1NOTUMHPGDALOX5APFEN1 | |
| SCHEMBL26672882 | 0.96 | OPRL1 (0.37) | OPRL1NOTUMHPGDALOX5APFEN1 | |
| SCHEMBL26672864 | 0.96 | OPRL1 (0.37) | OPRL1NOTUMHPGDALOX5APFEN1 | |
| SCHEMBL16768989 | 0.96 | OPRL1 (0.37) | OPRL1NOTUMHPGDALOX5APFEN1 | |
| SCHEMBL16769046 | 0.96 | OPRL1 (0.37) | OPRL1NOTUMHPGDALOX5APFEN1 | |
| SCHEMBL12018637 | 0.95 | OPRL1 (0.38) | OPRL1NOTUMHPGDFEN1HTR2C | |
| SCHEMBL26045594 | 0.95 | OPRL1 (0.38) | OPRL1NOTUMHPGDFEN1HTR2C | |
| SCHEMBL26672866 | 0.94 | NOTUM (0.35) | OPRL1NOTUMHPGDHTR2C | |
| SCHEMBL26802857 | 0.94 | NOTUM (0.35) | OPRL1NOTUMHPGDHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230383186-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-11-30 | — | — | US | disclosed |
| US-11762241-B2 | Device for the regulation of light transmission | MERCK PATENT GMBH (DE) | 2023-09-19 | — | — | US | disclosed |
| US-9517990-B2 | Negative dielectric anisotropic liquid crystal compounds containing 2,3-difluorophenyl group, and preparation method and use thereof | Shijiazhuang Chenzhi Yonghua Display Materials Co., Ltd. (CN) | 2016-12-13 | — | — | US | disclosed |
| US-9428693-B2 | Liquid crystal composition having negative dielectric anisotropy | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2016-08-30 | — | — | US | disclosed |
| US-20150184075-A1 | Liquid Crystal Composition Having Negative Dielectric Anisotropy | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2015-07-02 | — | — | US | disclosed |
| US-20150152330-A1 | Negative Dielectric Anisotropic Liquid Crystal Compounds Containing 2,3-Difluorophenyl Group, and Preparation Method and Use Thereof | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152330-A1 | Negative Dielectric Anisotropic Liquid Crystal Compounds Containing 2,3-Difluorophenyl Group, and Preparation Method and Use Thereof | CTNND1, YWHAZ, DVL1 | OPRL1 2889/4885NOTUM 1928/4885HPGD 4458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.