Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.51 |
| ▸ | CPS1 | P31327 | 2/20 | 0.37 |
| ▸ | HPGDS | O60760 | 3/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21043272 | 1.00 | GPR119 (0.51) | GPR119CPS1HPGDSCYP4F2CYP4A11 | |
| SCHEMBL16757751 | 0.92 | GPR119 (0.48) | GPR119HPGDSCYP4F2CYP4A11ROCK2 | |
| SCHEMBL16757749 | 0.92 | GPR119 (0.48) | GPR119HPGDSCYP4F2CYP4A11ROCK2 | |
| SCHEMBL18848863 | 0.91 | GPR119 (0.51) | GPR119CPS1HPGDSCYP4F2CYP4A11 | |
| SCHEMBL18848897 | 0.89 | GPR119 (0.52) | GPR119HPGDSCYP4F2CYP4A11HCRTR2 | |
| SCHEMBL16768927 | 0.89 | GPR119 (0.46) | GPR119HPGDSCYP4F2CYP4A11 | |
| SCHEMBL21043259 | 0.89 | GPR119 (0.46) | GPR119HPGDSCYP4F2CYP4A11 | |
| SCHEMBL15538497 | 0.88 | GPR119 (0.54) | GPR119HPGDSCYP4F2CYP4A11 | |
| SCHEMBL15538500 | 0.88 | GPR119 (0.54) | GPR119HPGDSCYP4F2CYP4A11 | |
| SCHEMBL15539417 | 0.87 | GPR119 (0.51) | GPR119HPGDSCYP4F2CYP4A11HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015080446-A1 | AMIDE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2015-06-04 | — | — | WO | disclosed |