Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | HPGDS | O60760 | 3/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 5/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.38 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16768927 | 1.00 | GPR119 (0.46) | GPR119HRH3HPGDSCYP4F2CYP4A11 | |
| SCHEMBL21043235 | 0.91 | GPR119 (0.44) | GPR119HRH3HPGDSCYP4F2CYP4A11 | |
| SCHEMBL16757838 | 0.91 | GPR119 (0.44) | GPR119HRH3HPGDSCYP4F2CYP4A11 | |
| SCHEMBL16757834 | 0.91 | GPR119 (0.44) | GPR119HRH3HPGDSCYP4F2CYP4A11 | |
| SCHEMBL16769045 | 0.89 | GPR119 (0.51) | GPR119HPGDSCYP4F2CYP4A11 | |
| SCHEMBL21043272 | 0.89 | GPR119 (0.51) | GPR119HPGDSCYP4F2CYP4A11 | |
| SCHEMBL16769011 | 0.87 | GPR119 (0.51) | GPR119HRH3HPGDSCYP4F2CYP4A11 | |
| SCHEMBL16769068 | 0.86 | ACHE (0.38) | GPR119HRH3 | |
| SCHEMBL15539327 | 0.86 | GPR119 (0.50) | GPR119HRH3HPGDSCYP4F2CYP4A11 | |
| SCHEMBL15539331 | 0.86 | GPR119 (0.50) | GPR119HRH3HPGDSCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074384-B1 | AMIDE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-05-22 | — | — | EP | disclosed |