Known targets — ChEMBL curated mechanism
CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8
The experimentally established mechanism targets of Phloroglucinol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phloroglucinol SCHEMBL30542958 | 0.78 | — | — | |
| Phloroglucinol SCHEMBL2889628 | 0.78 | BACE1 (1.00) | — | |
| Phloroglucinol SCHEMBL26311 | 0.78 | — | — | |
| Phloroglucinol SCHEMBL1913949 | 0.74 | BACE1 (0.89) | — | |
| Phloroglucinol SCHEMBL310716 | 0.74 | BACE1 (0.89) | — | |
| Phloroglucinol SCHEMBL23346245 | 0.74 | BACE1 (0.89) | — | |
| Phloroglucinol SCHEMBL5495237 | 0.74 | BACE1 (0.89) | — | |
| Phloroglucinol SCHEMBL502610 | 0.74 | BACE1 (0.89) | — | |
| Phloroglucinol SCHEMBL10916023 | 0.74 | BACE1 (0.89) | — | |
| Phloroglucinol SCHEMBL28934991 | 0.74 | BACE1 (0.89) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150150999-A1 | POLYMER-NSAID CONJUGATE | POLYACTIVA PTY LTD (AU) | 2015-06-04 | — | — | US | disclosed |