Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | GRN | P28799 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230173 | 0.85 | PTGS1 (0.38) | ATMSMN1; SMN2CYP1A2CYP2C19PTGS1 | |
| SCHEMBL16769783 | 0.82 | PTGS1 (0.40) | SMN1; SMN2CYP1A2CYP2C19PTGS1BRAF | |
| SCHEMBL17295614 | 0.78 | PTGS1 (0.34) | ATMSMN1; SMN2PTGS1MAPTALDH1A1 | |
| SCHEMBL17295611 | 0.77 | PTGS1 (0.33) | PTGS1 | |
| SCHEMBL17295617 | 0.77 | PTGS1 (0.33) | PTGS1BRAFMAPT | |
| SCHEMBL19077922 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP1A2MAPK1CYP2C19NPC1 | |
| SCHEMBL16769347 | 0.75 | SMN1; SMN2 (0.37) | SMN1; SMN2CYP1A2MAPK1CYP2C19PTGS1 | |
| SCHEMBL29247996 | 0.74 | POLB (0.44) | SMN1; SMN2PTGS1BRAFNPC1RAB9A | |
| SCHEMBL19087096 | 0.72 | PTGS1 (0.42) | SMN1; SMN2CYP1A2CYP2C19PTGS1BRAF | |
| SCHEMBL19087157 | 0.71 | CYP1A2 (0.47) | SMN1; SMN2CYP1A2MAPK1CYP2C19PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3148984-B1 | PROCESS FOR THE PREPARATION OF 5-FLUORO-1H-PYRAZOLES STARTING FROM HEXAFLUOROPROPENE | BAYER ANIMAL HEALTH GMBH (DE) | 2019-07-24 | — | — | EP | disclosed |
| EP-3183237-B1 | PROCESS FOR THE PREPARATION OF 5-FLUORO-1H-PYRAZOLES STARTING FROM HEXAFLUOROPROPENE | BAYER ANIMAL HEALTH GMBH (DE) | 2019-07-24 | — | — | EP | disclosed |
| US-9845312-B2 | Process for the preparation of 5-fluoro-1H-pyrazoles | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-12-19 | — | — | US | disclosed |
| US-9725415-B2 | Process for the preparation of 5-fluoro-1H-pyrazoles | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-08-08 | — | — | US | disclosed |
| US-20160289213-A1 | PROCESS FOR THE PREPARATION OF 5-FLUORO-1H-PYRAZOLES | ELANCO ANIMAL HEALTH GMBH (DE) | 2016-10-06 | — | — | US | disclosed |
| US-20160289194-A1 | PROCESS FOR THE PREPARATION OF 5-FLUORO-1H-PYRAZOLES | ELANCO ANIMAL HEALTH GMBH (DE) | 2016-10-06 | — | — | US | disclosed |
| US-9302994-B2 | Process for the preparation of 5-fluoro-1H-pyrazoles | BAYER CROPSCIENCE AG (DE) | 2016-04-05 | — | — | US | disclosed |
| US-20150152062-A1 | PROCESS FOR THE PREPARATION OF 5-FLUORO-1H-PYRAZOLES | ELANCO ANIMAL HEALTH GMBH (DE) | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152062-A1 | PROCESS FOR THE PREPARATION OF 5-FLUORO-1H-PYRAZOLES | CYP4F3, CYP2F1, CBR3 | ATM 3081/4885SMN1; SMN2 4640/4885CYP1A2 408/4885 |
| US-20160289194-A1 | PROCESS FOR THE PREPARATION OF 5-FLUORO-1H-PYRAZOLES | CYP2F1, CYP4F11, CYP3A5 | ATM 3089/4885SMN1; SMN2 4514/4885CYP1A2 18/4885 |
| US-20160289213-A1 | PROCESS FOR THE PREPARATION OF 5-FLUORO-1H-PYRAZOLES | CYP2F1, CYP4F11, CYP4F2 | ATM 3050/4885SMN1; SMN2 4453/4885CYP1A2 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.