Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19087096 | 0.81 | PTGS1 (0.42) | CYP1A2BRAFSMN1; SMN2HTTHPGD | |
| SCHEMBL13860574 | 0.79 | NPC1 (0.47) | CYP1A2BRAFKDM4EHPGDALDH1A1 | |
| SCHEMBL19077922 | 0.78 | SMN1; SMN2 (0.52) | CYP1A2SMN1; SMN2HTTKDM4EHPGD | |
| SCHEMBL16769783 | 0.77 | PTGS1 (0.40) | CYP1A2BRAFSMN1; SMN2HTTKDM4E | |
| SCHEMBL12609497 | 0.74 | PTGS1 (0.35) | CYP1A2BRAFMEN1KMT2APTGS1 | |
| SCHEMBL19087098 | 0.74 | MAPT (0.44) | CYP1A2BRAFSMN1; SMN2HTTKDM4E | |
| SCHEMBL15060859 | 0.73 | PTGS1 (0.37) | CYP1A2BRAFSMN1; SMN2HTTKDM4E | |
| SCHEMBL11400604 | 0.72 | SMN1; SMN2 (0.50) | SMN1; SMN2HTTKDM4EHPGDALDH1A1 | |
| SCHEMBL3835167 | 0.71 | HTT (0.64) | CYP1A2SMN1; SMN2HTTKDM4EALDH1A1 | |
| SCHEMBL16769348 | 0.71 | ATM (0.38) | CYP1A2BRAFSMN1; SMN2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957256-B2 | Process for the preparation of 5-fluoro-1H-pyrazoles starting from hexafluoropropene | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-05-01 | — | — | US | disclosed |
| US-20170190690-A1 | Process for the preparation of 5-fluoro-1H-pyrazoles starting from hexafluoropropene | ELANCO ANIMAL HEALTH GMBH (DE) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190690-A1 | Process for the preparation of 5-fluoro-1H-pyrazoles starting from hexafluoropropene | CYP2F1, CYP4F2, CYP4F11 | CYP1A2 26/4885BRAF 84/4885SMN1; SMN2 3769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.