Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.54 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.54 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.45 |
| ▸ | LCAT | P04180 | 1/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | OGA | O60502 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 3/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NNMT | P40261 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1441410 | 0.89 | CHRNB2 (0.54) | CHRNB2CHRNA4CHRNB4CHRNA3PIK3CG | |
| SCHEMBL26094391 | 0.88 | CHRNB2 (0.53) | CHRNB2CHRNA4CHRNB4CHRNA3PIK3CG | |
| SCHEMBL16769746 | 0.85 | ACACB (0.56) | CHRNB2CHRNA4CHRNB4CHRNA3LCAT | |
| SCHEMBL16769749 | 0.84 | ACACB (0.57) | LCATACACB | |
| SCHEMBL16769744 | 0.84 | LCAT (0.47) | CHRNB2CHRNA4CHRNB4CHRNA3LCAT | |
| SCHEMBL4389854 | 0.83 | MAPT (0.57) | CHRNB2CHRNA4CHRNB4CHRNA3MAPT | |
| SCHEMBL4391755 | 0.80 | CHRNB2 (0.58) | CHRNB2CHRNA4CHRNB4CHRNA3PIK3CG | |
| SCHEMBL21397330 | 0.80 | CHRNB2 (0.59) | CHRNB2CHRNA4CHRNB4CHRNA3LCAT | |
| SCHEMBL21384592 | 0.79 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRNB4CHRNA3PIK3CG | |
| SCHEMBL30574420 | 0.79 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRNB4CHRNA3PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150575-B2 | Piperidinylpyrazolopyridine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-10-06 | — | — | US | disclosed |
| US-20150152102-A1 | PIPERIDINYLPYRAZOLOPYRIDINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152102-A1 | PIPERIDINYLPYRAZOLOPYRIDINE DERIVATIVE | LCAT, LPL, LCLAT1 | CHRNB2 3937/4885CHRNA4 3753/4885CHRNB4 4086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.