SCHEMBL16769859

SCHEMBL16769859

c1ccc2c(c1)c1ccccc1n2-c1ccc(-n2c3ccc(-n4c5ccccc5c5ccccc54)cc3c3cccnc32)cc1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.47
ATM Q13315 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
FEN1 P39748 1/20 0.41
ALDH1A1 P00352 1/20 0.40
TSHR P16473 1/20 0.40
CYP2C19 P33261 1/20 0.40
PDE4A P27815 6/20 0.38
PDE4B Q07343 5/20 0.38
PDE4C Q08493 5/20 0.38
PDE4D Q08499 5/20 0.38
LDHA P00338 1/20 0.35
PDE10A Q9Y233 1/20 0.34
PDE1A P54750 1/20 0.33
PDE1B Q01064 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20184179 1.00 KDM4E (0.47) KDM4EATML3MBTL1FEN1ALDH1A1
SCHEMBL25847041 0.97 KDM4E (0.53) KDM4EATML3MBTL1FEN1ALDH1A1
SCHEMBL26329814 0.94 KDM4E (0.50) KDM4EATML3MBTL1FEN1ALDH1A1
SCHEMBL5021434 0.94 KDM4E (0.44) KDM4EATML3MBTL1FEN1ALDH1A1
SCHEMBL25847043 0.94 KDM4E (0.44) KDM4EATML3MBTL1FEN1ALDH1A1
SCHEMBL17676394 0.93 KDM4E (0.49) KDM4EATML3MBTL1FEN1ALDH1A1
SCHEMBL17676387 0.93 KDM4E (0.49) KDM4EATML3MBTL1FEN1ALDH1A1
SCHEMBL26329788 0.93 KDM4E (0.49) KDM4EATML3MBTL1FEN1ALDH1A1
SCHEMBL19726482 0.92 KDM4E (0.48) KDM4EATML3MBTL1FEN1ALDH1A1
SCHEMBL24988436 0.91 KDM4E (0.42) KDM4EATML3MBTL1FEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9240559-B2 Phosphorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2016-01-19 US disclosed
US-9240559-B2 Phosphorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2016-01-19 US disclosed
US-20150236275-A1 Phosphorescent Compound and Organic Electroluminescent Device Using the Same LG DISPLAY CO., LTD. (KR) 2015-08-20 US disclosed
US-20150236275-A1 Phosphorescent Compound and Organic Electroluminescent Device Using the Same LG DISPLAY CO., LTD. (KR) 2015-08-20 US disclosed
US-9045471-B2 Phosphorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2015-06-02 US disclosed
US-9045471-B2 Phosphorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2015-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150236275-A1 Phosphorescent Compound and Organic Electroluminescent Device Using the Same PTH1R, PGLS, PPIP5K2 KDM4E 3639/4885ATM 2438/4885L3MBTL1 3871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.