Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.65 |
| ▸ | CTSL | P07711 | 5/20 | 0.61 |
| ▸ | CTSS | P25774 | 3/20 | 0.61 |
| ▸ | CTSB | P07858 | 1/20 | 0.61 |
| ▸ | MMP3 | P08254 | 1/20 | 0.61 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.59 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13589982 | 0.91 | CTSK (0.64) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL5827200 | 0.91 | CTSK (0.67) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL14433713 | 0.91 | CTSK (0.64) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL31094975 | 0.91 | CTSK (0.67) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL13888706 | 0.90 | CTSK (0.79) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6945614 | 0.90 | CTSK (0.79) | CTSKCTSLCTSSCTSB | |
| SCHEMBL1175268 | 0.90 | CTSK (0.79) | CTSKCTSLCTSSCTSB | |
| SCHEMBL19190688 | 0.88 | CTSK (0.69) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL8014485 | 0.88 | CAPN1 (0.72) | CTSKCTSLCTSSCTSBMMP3 | |
| SCHEMBL31729514 | 0.87 | CAPN1 (0.68) | CTSKCTSLCTSSCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045524-B2 | Selective caspase inhibitors and uses thereof | NOVAGENESIS FOUNDATION (CH) | 2015-06-02 | — | — | US | disclosed |