Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 7/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 3/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL525953 | 0.89 | CYSLTR2 (0.38) | CYSLTR2CYSLTR1CA2CA1PDE3B | |
| SCHEMBL526245 | 0.87 | CA2 (0.32) | CA2CA1PDE3BPDE3AP2RY12 | |
| SCHEMBL16770358 | 0.80 | GABRA1 (0.34) | CA2 | |
| SCHEMBL13008103 | 0.74 | DYRK1A (0.37) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL525915 | 0.74 | CYSLTR2 (0.40) | CYSLTR2CYSLTR1PDE3BPDE3AP2RY12 | |
| SCHEMBL16770359 | 0.74 | CA2 (0.32) | CA2 | |
| SCHEMBL14973639 | 0.73 | PDE3B (0.34) | CYSLTR2CYSLTR1CA2PDE3BPDE3A | |
| SCHEMBL13008114 | 0.73 | PDE3B (0.42) | CYSLTR2CYSLTR1PDE3BPDE3AP2RY12 | |
| SCHEMBL18900388 | 0.72 | HPRT1 (0.32) | CA2CA1PDE3BPDE3AP2RY12 | |
| SCHEMBL525626 | 0.72 | PDE3B (0.34) | CA2PDE3BPDE3AP2RY12PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598507-B1 | ANTICANCER DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2017-05-31 | — | — | EP | disclosed |
| US-9056914-B2 | Anticancer derivatives, preparation thereof and therapeutic use thereof | SANOFI (FR) | 2015-06-16 | — | — | US | disclosed |