SCHEMBL16772247

SCHEMBL16772247

C[C@@H]1CC1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PPM1D O15297 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15979224 0.79
SCHEMBL19516622 0.78
SCHEMBL19516621 0.78
SCHEMBL19517992 0.78
SCHEMBL20671512 0.76
SCHEMBL17864876 0.76
SCHEMBL15032469 0.75 CA2 (0.33) PPM1D
SCHEMBL1235913 0.73
SCHEMBL956313 0.73
SCHEMBL17865055 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9163078-B2 Regulators of NFAT CHILDREN'S MEDICAL CENTER CORPORATION (US) 2015-10-20 US disclosed
US-9045763-B2 Linear donor constructs for targeted integration SANGAMO BIOSCIENCES, INC. (US) 2015-06-02 US disclosed