SCHEMBL16772247

SCHEMBL16772247

C[C@@H]1CC1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ PPM1D O15297 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15979224 0.79 — —
SCHEMBL19516622 0.78 — —
SCHEMBL19516621 0.78 — —
SCHEMBL19517992 0.78 — —
SCHEMBL20671512 0.76 — —
SCHEMBL17864876 0.76 — —
SCHEMBL15032469 0.75 CA2 (0.33) PPM1D
SCHEMBL17865055 0.73 — —
SCHEMBL956313 0.73 — —
SCHEMBL1235913 0.73 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9163078-B2 Regulators of NFAT CHILDREN'S MEDICAL CENTER CORPORATION (US) 2015-10-20 — — US disclosed
US-9045763-B2 Linear donor constructs for targeted integration SANGAMO BIOSCIENCES, INC. (US) 2015-06-02 — — US disclosed
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