Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
| ▸ | PPM1D | O15297 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5380472 | 0.75 | NPY1R (0.38) | GSRPPM1D | |
| SCHEMBL7464146 | 0.75 | NPY1R (0.38) | GSRPPM1D | |
| SCHEMBL5380480 | 0.75 | NPY1R (0.38) | GSRPPM1D | |
| SCHEMBL13573044 | 0.75 | NPY1R (0.41) | CA2GSRPPM1D | |
| SCHEMBL7464139 | 0.75 | NPY1R (0.38) | GSRPPM1D | |
| SCHEMBL16554702 | 0.75 | PPM1D (0.32) | PPM1D | |
| SCHEMBL16799031 | 0.75 | PPM1D (0.32) | PPM1D | |
| SCHEMBL5380476 | 0.75 | NPY1R (0.38) | GSRPPM1D | |
| SCHEMBL14861352 | 0.75 | PPM1D (0.32) | PPM1D | |
| SCHEMBL16772247 | 0.75 | PPM1D (0.30) | PPM1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2550285-B1 | TRIOXACARCINS AND USES THEREOF | HARVARD COLLEGE (US) | 2017-07-19 | — | — | EP | disclosed |
| US-9611287-B2 | Trioxacarcins and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-04-04 | — | — | US | disclosed |
| US-20160355537-A1 | TRIOXACARCINS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-12-08 | — | — | US | disclosed |
| US-9102697-B2 | Trioxacarcins and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-08-11 | — | — | US | disclosed |
| US-9102697-B2 | Trioxacarcins and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-08-11 | — | — | US | disclosed |
| US-20130150314-A1 | TRIOXACARCINS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160355537-A1 | TRIOXACARCINS AND USES THEREOF | PCSK9, PCSK7, PCSK6 | CA2 1737/4885GSR 689/4885PPM1D 2284/4885 |
| US-20130150314-A1 | TRIOXACARCINS AND USES THEREOF | PCSK9, PCSK7, ABCC9 | CA2 1601/4885GSR 717/4885PPM1D 2250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.