Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20680673 | 0.88 | HDAC6 (0.42) | SMN1; SMN2RAB9ADUSP3L3MBTL1HDAC6 | |
| SCHEMBL9917430 | 0.87 | HDAC6 (0.57) | HDAC6KMT2AMEN1ERBB2HDAC8 | |
| SCHEMBL1128943 | 0.85 | HDAC8 (0.50) | SMN1; SMN2HDAC6IDO1KMT2AMEN1 | |
| SCHEMBL662061 | 0.85 | IDO1 (0.45) | SMN1; SMN2RAB9AHDAC6IDO1NPC1 | |
| SCHEMBL9917423 | 0.81 | RAB9A (0.41) | SMN1; SMN2RAB9ADUSP3L3MBTL1HDAC6 | |
| SCHEMBL9917429 | 0.81 | RAB9A (0.41) | SMN1; SMN2RAB9ADUSP3L3MBTL1HDAC6 | |
| SCHEMBL9917422 | 0.81 | HDAC6 (0.54) | SMN1; SMN2RAB9ADUSP3L3MBTL1HDAC6 | |
| SCHEMBL16418008 | 0.80 | RAB9A (0.44) | SMN1; SMN2RAB9ADUSP3L3MBTL1HDAC6 | |
| SCHEMBL13042 | 0.79 | NPC1 (0.50) | SMN1; SMN2RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL6840368 | 0.78 | KDM4E (0.47) | SMN1; SMN2RAB9ADUSP3L3MBTL1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150152064-A1 | METHODS AND COMPOSITIONS OF TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152064-A1 | METHODS AND COMPOSITIONS OF TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION | EIF2AK2, NSUN3, NSUN2 | SMN1; SMN2 2247/4885RAB9A 2617/4885DUSP3 358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.