Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.64 |
| ▸ | GRIA2 | P42262 | 6/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.46 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6513331 | 0.84 | GRIA4 (0.54) | KDM1AKIF11ACLYMCL1GRIA4 | |
| SCHEMBL4099446 | 0.83 | KEAP1 (0.58) | KDM1AGRIA4CA2CA9 | |
| SCHEMBL13977422 | 0.82 | KDM1A (0.71) | KDM1AGRIA2KCNH2KIF11AAK1 | |
| SCHEMBL4952483 | 0.80 | KDM1A (0.55) | KDM1AGRIA2KCNH2AAK1MCL1 | |
| SCHEMBL21092440 | 0.80 | KIF11 (0.69) | KDM1AKIF11 | |
| SCHEMBL526506 | 0.79 | KDM1A (1.00) | KDM1AGRIA2KCNH2 | |
| SCHEMBL526505 | 0.79 | KDM1A (1.00) | KDM1AGRIA2KCNH2 | |
| SCHEMBL15136917 | 0.79 | KDM1A (1.00) | KDM1AGRIA2KCNH2 | |
| SCHEMBL13468554 | 0.79 | HPGD (0.51) | KDM1ASYK | |
| Hydrochloric Acid SCHEMBL527300 | 0.78 | KDM1A (0.98) | KDM1AGRIA2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110092553-A1 | Substituted Azole Derivatives, Compositions, and Methods of Use | TRANSTECH PHARMA, INC. (US) | 2011-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092553-A1 | Substituted Azole Derivatives, Compositions, and Methods of Use | PTPRO, PTPN5, PTPRE | KDM1A 542/4885GRIA2 3938/4885KCNH2 2900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.