SCHEMBL16772465

SCHEMBL16772465

O=S1Oc2ccc3ccccc3c2-c2c(ccc3ccccc23)O1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.53
ALDH1A1 P00352 5/20 0.42
HSD17B10 Q99714 4/20 0.42
TSHR P16473 2/20 0.42
CYP2A6 P11509 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
WDR5 P61964 1/20 0.41
KDM4E B2RXH2 4/20 0.41
MAPT P10636 2/20 0.41
CYP19A1 P11511 1/20 0.41
NPC1 O15118 1/20 0.41
GAA P10253 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
DNMT1 P26358 1/20 0.40
HPGD P15428 2/20 0.40
CYP1A2 P05177 1/20 0.40
GLA P06280 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16772619 0.74 ERN1 (0.39) GPR84ALDH1A1CYP2A6KDM4EMAPT
SCHEMBL1777121 0.72 GPR84 (0.53) GPR84ALDH1A1HSD17B10TSHRCYP2A6
SCHEMBL30428179 0.72 GPR84 (0.53) GPR84ALDH1A1HSD17B10TSHRCYP2A6
SCHEMBL30901145 0.72 GPR84 (0.53) GPR84ALDH1A1HSD17B10TSHRCYP2A6
SCHEMBL22664856 0.72 GPR84 (0.53) GPR84ALDH1A1HSD17B10TSHRCYP2A6
SCHEMBL5899656 0.71 GPR84 (0.52) GPR84ALDH1A1HSD17B10TSHRCYP2A6
SCHEMBL8231432 0.71 GPR84 (0.52) GPR84ALDH1A1HSD17B10TSHRCYP2A6
SCHEMBL888325 0.71 GPR84 (0.52) GPR84ALDH1A1HSD17B10TSHRCYP2A6
SCHEMBL9782961 0.71 GPR84 (0.52) GPR84ALDH1A1HSD17B10TSHRCYP2A6
SCHEMBL2100200 0.70 HSP90AA1 (0.44) ALDH1A1HSD17B10TSHRTDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10007042-B2 Composition, light reflecting film, luminance-improving film, backlight unit, and liquid crystal display device FUJIFILM CORPORATION (JP) 2018-06-26 US disclosed
US-20170010398-A1 COMPOSITION, LIGHT REFLECTING FILM, LUMINANCE-IMPROVING FILM, BACKLIGHT UNIT, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-01-12 US disclosed
US-20170010398-A1 COMPOSITION, LIGHT REFLECTING FILM, LUMINANCE-IMPROVING FILM, BACKLIGHT UNIT, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-01-12 US disclosed
US-9416318-B2 Liquid crystal composition, polymer, film, and cholesteric liquid crystal FUJIFILM CORPORATION (JP) 2016-08-16 US disclosed
US-9416318-B2 Liquid crystal composition, polymer, film, and cholesteric liquid crystal FUJIFILM CORPORATION (JP) 2016-08-16 US disclosed
US-20150152332-A1 LIQUID CRYSTAL COMPOSITION, POLYMER, FILM, AND CHOLESTERIC LIQUID CRYSTAL FUJIFILM CORPORATION (JP) 2015-06-04 US disclosed
US-20150152332-A1 LIQUID CRYSTAL COMPOSITION, POLYMER, FILM, AND CHOLESTERIC LIQUID CRYSTAL FUJIFILM CORPORATION (JP) 2015-06-04 US disclosed