SCHEMBL1777121

SCHEMBL1777121

O=S1(=O)Oc2ccc3ccccc3c2-c2c(ccc3ccccc23)O1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.53
CA12 O43570 1/20 0.50
CA9 Q16790 1/20 0.50
ALDH1A1 P00352 5/20 0.42
HSD17B10 Q99714 3/20 0.42
TSHR P16473 2/20 0.42
CYP2A6 P11509 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
WDR5 P61964 1/20 0.41
KDM4E B2RXH2 5/20 0.41
MAPT P10636 3/20 0.41
CYP19A1 P11511 1/20 0.41
NPC1 O15118 1/20 0.41
GAA P10253 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
DNMT1 P26358 1/20 0.40
HPGD P15428 3/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2C9 P11712 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30901145 1.00 GPR84 (0.53) GPR84CA12CA9ALDH1A1HSD17B10
SCHEMBL1778091 0.74 CA12 (0.40) GPR84CA12CA9ALDH1A1CYP2A6
SCHEMBL12600566 0.74 ALDH1A1 (0.41) GPR84CA12CA9ALDH1A1HSD17B10
SCHEMBL114546 0.72 CA12 (0.50) GPR84CA12CA9ALDH1A1HSD17B10
SCHEMBL16772465 0.72 GPR84 (0.53) GPR84CA12CA9ALDH1A1HSD17B10
SCHEMBL22664856 0.72 GPR84 (0.53) GPR84CA12CA9ALDH1A1HSD17B10
SCHEMBL29448134 0.72 CA12 (0.50) GPR84CA12CA9ALDH1A1HSD17B10
SCHEMBL30428179 0.72 GPR84 (0.53) GPR84CA12CA9ALDH1A1HSD17B10
SCHEMBL21034460 0.72 MEN1 (0.43) CA12CA9ALDH1A1HSD17B10CYP2A6
SCHEMBL888325 0.71 GPR84 (0.52) GPR84CA12CA9ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12390424-B2 Sulfur (VI) fluoride compounds and methods for the preparation thereof THE SCRIPPS RESEARCH INSTITUTE (US) 2025-08-19 US disclosed
EP-4295841-A2 SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION The Scripps Research Institute (US) 2023-12-27 EP disclosed
EP-3892610-B1 SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION SCRIPPS RESEARCH INST (US) 2023-08-16 EP disclosed
US-20220000799-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF THE SCRIPPS RESEARCH INSTITUTE (US) 2022-01-06 US disclosed
EP-3892610-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE AS SCREENING AGENT The Scripps Research Institute (US) 2021-10-13 EP disclosed
US-11141385-B2 Sulfur (VI) fluoride compounds and methods for the preparation thereof THE SCRIPPS RESEARCH INSTITUTE (US) 2021-10-12 US disclosed
EP-3151817-B1 SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF SCRIPPS RESEARCH INST (US) 2021-03-03 EP disclosed
US-20200397719-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF THE SCRIPPS RESEARCH INSTITUTE (US) 2020-12-24 US disclosed
US-10765645-B2 Sulfur(VI) fluoride compounds and methods for the preparation thereof THE SCRIPPS RESEARCH INSTITUTE (US) 2020-09-08 US disclosed
US-20190029972-A1 SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF THE SCRIPPS RESEARCH INSTITUTE (US) 2019-01-31 US disclosed
US-10117840-B2 Sulfur(VI) fluoride compounds and methods for the preparation thereof THE SCRIPPS RESEARCH INSTITUTE (US) 2018-11-06 US disclosed
US-20170196985-A1 SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF THE SCRIPPS RESEARCH INSTITUTE 2017-07-13 US disclosed
US-9416318-B2 Liquid crystal composition, polymer, film, and cholesteric liquid crystal FUJIFILM CORPORATION (JP) 2016-08-16 US disclosed
US-9416318-B2 Liquid crystal composition, polymer, film, and cholesteric liquid crystal FUJIFILM CORPORATION (JP) 2016-08-16 US disclosed
US-20150152332-A1 LIQUID CRYSTAL COMPOSITION, POLYMER, FILM, AND CHOLESTERIC LIQUID CRYSTAL FUJIFILM CORPORATION (JP) 2015-06-04 US disclosed
US-20150152332-A1 LIQUID CRYSTAL COMPOSITION, POLYMER, FILM, AND CHOLESTERIC LIQUID CRYSTAL FUJIFILM CORPORATION (JP) 2015-06-04 US disclosed
EP-2004622-B1 CHIRAL BINAPHTHYL SULFATES FOR USE AS LIQUID CRYSTAL MATERIALS MERCK PATENT GMBH (DE) 2011-12-14 EP disclosed
US-7943061-B2 Chiral binaphthyl sulfates for use as liquid crystal materials MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-05-17 US disclosed
US-20100019199-A1 CHIRAL BINAPHTHYL SULFATES FOR USE AS LIQUID CRYSTAL MATERIALS MERCK PATENT GESELLSCHAFT (DE) 2010-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170196985-A1 SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF CYP2F1, NAF1, CYP2S1 GPR84 4097/4885CA12 678/4885CA9 238/4885
US-10765645-B2 Sulfur(VI) fluoride compounds and methods for the preparation thereof HAX1, CYP2F1, CYP4X1 GPR84 3894/4885CA12 618/4885CA9 248/4885
US-12390424-B2 Sulfur (VI) fluoride compounds and methods for the preparation thereof GRB2, SCTR, OGFR GPR84 646/4885CA12 485/4885CA9 1140/4885
US-20220000799-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF PTMS, IGF2R, SCTR GPR84 1167/4885CA12 662/4885CA9 1434/4885
US-20190029972-A1 SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF HAX1, CYP2F1, CYP4X1 GPR84 3894/4885CA12 618/4885CA9 248/4885
US-20200397719-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF CYP2F1, CYP2S1, NAF1 GPR84 4132/4885CA12 688/4885CA9 193/4885
US-20100019199-A1 CHIRAL BINAPHTHYL SULFATES FOR USE AS LIQUID CRYSTAL MATERIALS DVL3, DVL1, EBPL GPR84 4378/4885CA12 591/4885CA9 1254/4885
US-11141385-B2 Sulfur (VI) fluoride compounds and methods for the preparation thereof CYP2F1, CYP2S1, NAF1 GPR84 4132/4885CA12 688/4885CA9 193/4885
US-10117840-B2 Sulfur(VI) fluoride compounds and methods for the preparation thereof CYP2F1, NAF1, CYP2S1 GPR84 4097/4885CA12 678/4885CA9 238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.