Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | GLA | P06280 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26060033 | 0.98 | HSP90AA1 (0.32) | HSP90AA1HSP90AB1KDM4EALDH1A1MAPT | |
| SCHEMBL27048452 | 0.94 | PGR (0.32) | HSP90AA1HSP90AB1KDM4EALDH1A1MAPT | |
| SCHEMBL9916905 | 0.94 | HSP90AA1 (0.36) | HSP90AA1HSP90AB1KDM4EALDH1A1MAPT | |
| SCHEMBL9916908 | 0.94 | HSP90AA1 (0.36) | HSP90AA1HSP90AB1KDM4EALDH1A1MAPT | |
| SCHEMBL9916918 | 0.94 | HSP90AA1 (0.36) | HSP90AA1HSP90AB1KDM4EALDH1A1MAPT | |
| SCHEMBL24658066 | 0.93 | ABCG2 (0.32) | HSP90AA1HSP90AB1KMT2ACASP3SENP7 | |
| SCHEMBL26060032 | 0.93 | HCRTR1 (0.31) | — | |
| SCHEMBL25875885 | 0.93 | HSP90AA1 (0.33) | HSP90AA1HSP90AB1CASP3SENP7SENP6 | |
| SCHEMBL17126417 | 0.93 | HSP90AA1 (0.34) | HSP90AA1HSP90AB1KDM4EALDH1A1MAPT | |
| SCHEMBL31504676 | 0.93 | LPL (0.34) | HSP90AA1HSP90AB1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10446759-B2 | Phenanthrene compounds for organic electronic devices | MERCK PATENT GMBH (DE) | 2019-10-15 | — | — | US | disclosed |
| EP-2858980-B1 | PHENANTHRENES FOR USE IN ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-06-26 | — | — | EP | disclosed |
| US-20180102479-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-04-12 | — | — | US | disclosed |
| US-20180102479-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-04-12 | — | — | US | disclosed |
| US-9799833-B2 | Phenanthrene compounds for organic electronic devices | MERCK PATENT GMBH (DE) | 2017-10-24 | — | — | US | disclosed |
| US-9799833-B2 | Phenanthrene compounds for organic electronic devices | MERCK PATENT GMBH (DE) | 2017-10-24 | — | — | US | disclosed |
| US-20150155491-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-06-04 | — | — | US | disclosed |
| US-20150155491-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10446759-B2 | Phenanthrene compounds for organic electronic devices | PAH, CYP1A1, AHR | HSP90AA1 3865/4885HSP90AB1 4220/4885KDM4E 1217/4885 |
| US-20150155491-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | PAH, CYP1A1, AHR | HSP90AA1 3865/4885HSP90AB1 4220/4885KDM4E 1217/4885 |
| US-20180102479-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | PAH, CYP1A1, AHR | HSP90AA1 3865/4885HSP90AB1 4220/4885KDM4E 1217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.