Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29289096 | 0.90 | KDM4E (0.50) | KDM4ELMNAL3MBTL1TDP1KMT2A | |
| SCHEMBL8378527 | 0.90 | KDM4E (0.50) | KDM4ELMNAL3MBTL1TDP1KMT2A | |
| SCHEMBL11406784 | 0.86 | KDM4E (0.45) | KDM4ELMNAL3MBTL1TDP1KMT2A | |
| SCHEMBL11405516 | 0.86 | KDM4E (0.45) | KDM4ELMNAL3MBTL1TDP1KMT2A | |
| Mannitol SCHEMBL14639192 | 0.84 | LMNA (0.52) | KDM4ELMNAL3MBTL1TDP1MEN1 | |
| SCHEMBL12220094 | 0.83 | KDM4E (0.40) | KDM4ELMNAL3MBTL1TDP1 | |
| SCHEMBL19873268 | 0.83 | KDM4E (0.47) | KDM4ELMNAL3MBTL1TDP1RECQL | |
| SCHEMBL8376708 | 0.83 | KDM4E (0.47) | KDM4ELMNAL3MBTL1TDP1RECQL | |
| SCHEMBL9110197 | 0.83 | KDM4E (0.47) | KDM4ELMNAL3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL7686602 | 0.81 | KDM4E (0.39) | KDM4ELMNAL3MBTL1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051418-B2 | Glucose-PEG conjugates for reducing glucose transport into a cell | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-06-09 | — | — | US | disclosed |