Mannitol

Mannitol

SCHEMBL14639192

COCCOCCOCCOCCOC.OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
TDP1 Q9NUW8 1/20 0.50
KDM4E B2RXH2 2/20 0.43
PDE4A P27815 1/20 0.38
USP2 O75604 1/20 0.35
SLCO1B1 Q9Y6L6 1/20 0.35
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TOP1 P11387 1/20 0.32
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16775495 0.84 KDM4E (0.44) LMNAL3MBTL1TDP1KDM4EMEN1
SCHEMBL24864413 0.84 LMNA (0.37) LMNAL3MBTL1TDP1KDM4ETOP1
SCHEMBL28531820 0.80 LMNA (0.46) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL2297555 0.80 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL1964137 0.80 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL6700235 0.80 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL92729 0.80 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL19741239 0.80 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL1668363 0.80 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL4996629 0.80 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210088535-A1 PHOTONIC BLOOD TYPING UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2021-03-25 US disclosed
US-20200408785-A1 PHOTONIC PATHOGEN DETECTION UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2020-12-31 US disclosed
US-10794921-B2 Photonic blood typing UNIVERSITY OF WASHINGTON (US) 2020-10-06 US disclosed
US-20190154683-A1 HIERARCHICAL FILMS HAVING ULTRA LOW FOULING AND HIGH RECOGNITION ELEMENT LOADING PROPERTIES UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2019-05-23 US disclosed
US-20190041410-A1 PHOTONIC BLOOD TYPING UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2019-02-07 US disclosed
US-10073102-B2 Photonic blood typing UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2018-09-11 US disclosed
US-10031138-B2 Hierarchical films having ultra low fouling and high recognition element loading properties UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2018-07-24 US disclosed
US-20170227555-A1 PHOTONIC BLOOD TYPING UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2017-08-10 US disclosed
EP-2734841-B1 PHOTONIC BLOOD TYPING UNIV WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2017-07-05 EP disclosed
US-9599613-B2 Photonic blood typing UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2017-03-21 US disclosed
US-20140315760-A1 PHOTONIC BLOOD TYPING PUGET SOUND BLOOD CENTER (US) 2014-10-23 US disclosed
EP-2734841-A2 PHOTONIC BLOOD TYPING University of Washington Through Its Center for Comercialization (US) 2014-05-28 EP disclosed
US-20130244249-A1 HIERARCHICAL FILMS HAVING ULTRA LOW FOULING AND HIGH RECOGNITION ELEMENT LOADING PROPERTIES DEFENSE THREAT REDUCTION AGENCY, US DOD 2013-09-19 US disclosed
WO-2013013220-A2 PHOTONIC BLOOD TYPING UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2013-01-24 WO disclosed