SCHEMBL167789

SCHEMBL167789

Brc1cncnc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL16039940 0.96
SCHEMBL7892975 0.96
Bromide SCHEMBL11861598 0.96
Fluoromethane SCHEMBL28138428 0.90
SCHEMBL29516680 0.83 HCAR2 (0.33)
Carbamic Acid SCHEMBL17997306 0.81 HCAR2 (0.48)
SCHEMBL998973 0.74 DYRK1A (0.42)
SCHEMBL998922 0.70 ATM (0.56)
SCHEMBL4974 0.69
SCHEMBL2814958 0.67 ATM (0.65)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4052 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025129105-A1 COMPOSITION AND METHOD FOR DETECTION OF BIOMOLECULES VIA AROMATIC LABELING USING HETEROCYCLIC COMPOUNDS Life Technologies Corporation (US) 2025-06-19 WO claimed
CN-119684617-A Two-dimensional metal organic layer based on multi-nitrogen ligand, and preparation method and application thereof 浙江大学 2025-03-25 CN claimed
CN-119613346-A Method for preparing 5-bromopyrimidine 上海沃缨生物科技有限公司 2025-03-14 CN claimed
CN-118146210-A Organic molecular additive and preparation method and application thereof 正泰新能科技股份有限公司 2024-06-07 CN claimed
CN-117865898-A Preparation method of 5-bromopyrimidine 常州琦诺生物科技有限公司 2024-04-12 CN claimed
US-20230416281-A1 METHOD FOR PRODUCING (2-METHYLPYRIMIDIN-5-YL)BORONIC ACID DERIVATIVE KANEKA CORPORATION (JP) 2023-12-28 US claimed
CN-117203212-A Process for producing (2-methylpyrimidin-5-yl) boric acid derivative 株式会社钟化 2023-12-08 CN claimed
US-20230263801-A1 COMBINATION THERAPY OF PARP INHIBITORS Impact Therapeutics (Shanghai), Inc (CN) 2023-08-24 US claimed
CN-116322680-A Combination regimens for PARP inhibitors 上海瑛派药业有限公司 2023-06-23 CN claimed
EP-4185295-A1 COMBINATION THERAPY OF PARP INHIBITORS Impact Therapeutics (Shanghai), Inc (CN) 2023-05-31 EP claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0029282-B1 PROCESS FOR PREPARING 5-HALOPYRIMIDINES AND 5-PYRIMIDINE METHANOLS ELI LILLY AND COMPANY (US) 1983-05-18 EP claimed
EP-0029282-A1 Process for preparing 5-halopyrimidines and 5-pyrimidine methanols ELI LILLY AND COMPANY (US) 1981-05-27 EP claimed
US-4252955-A FROM 4-HALO-5-HYDROXY-2(5H)-FURANONES AND FORMAMIDE AT HIGH TEMPERATURE ELI LILLY AND COMPANY (US) 1981-02-24 US claimed