Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6682176 | 0.86 | ATM (0.72) | ATMNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28209270 | 0.80 | ATM (0.46) | ATMNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL12302096 | 0.76 | ALDH1A1 (0.73) | ATMNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL1673427 | 0.76 | ALDH1A1 (0.73) | ATMNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL2814958 | 0.76 | ATM (0.65) | ATMALDH1A1CYP2A6XDHCYP11B1 | |
| SCHEMBL68094 | 0.76 | ALDH1A1 (0.73) | ATMNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL1000061 | 0.75 | CYP2A6 (0.48) | ATMNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL5719996 | 0.75 | ERN1 (0.45) | ATMSMN1; SMN2ALDH1A1CYP2A6XDH | |
| SCHEMBL4966225 | 0.74 | ALDH1A1 (0.58) | ATMNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22418964 | 0.74 | ATM (0.44) | ATMCYP2A6XDHCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504609-A | Alpraxitans an intermediate compound of (C) Alpraxitans and preparation method thereof | 成都启晟合研医药科技有限公司 | 2025-02-25 | — | — | CN | disclosed |
| US-20230019129-A1 | HEPATITIS B CORE PROTEIN ALLOSTERIC MODULATORS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2023-01-19 | — | — | US | disclosed |
| CN-111848514-B | Chiral organic luminescent material and application thereof | 深圳大学 | 2022-05-20 | — | — | CN | disclosed |
| CN-109309166-B | Organic electroluminescent device and anthracene compound containing 2,6,9, 10-tetra-substitution | 北京鼎材科技有限公司 | 2022-05-20 | — | — | CN | disclosed |
| EP-3974426-A1 | HEPATITIS B CORE PROTEIN ALLOSTERIC MODULATORS | Indiana University Research and Technology Corporation (US) | 2022-03-30 | — | — | EP | disclosed |
| US-10947224-B2 | Hepatitis B core protein allosteric modulators | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2021-03-16 | — | — | US | disclosed |
| US-10892419-B2 | Space-through charge transfer compound, and organic light emitting diode and display device using the same | LG DISPLAY CO., LTD. (KR) | 2021-01-12 | — | — | US | disclosed |
| CN-106413402-B | Hepatitis b core protein allosteric modulators | 美国印第安纳大学研究和技术公司 | 2020-10-30 | — | — | CN | disclosed |
| CN-111848514-A | Chiral organic luminescent material and application thereof | 深圳大学 | 2020-10-30 | — | — | CN | disclosed |
| US-20200331906-A1 | COMPOUND, METHOD OF SYNTHESIZING COMPOUND WITH PYRIDINE RING AND LIGHT-EMITTING ELEMENT | AU OPTRONICS CORPORATION (TW) | 2020-10-22 | — | — | US | disclosed |
| EP-1423386-A1 | THIOPHENYLTHIOPYRANE DIOXIDES AS MMP OR TNF-ALPHA INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-02 | — | — | EP | disclosed |
| WO-2003022842-A1 | THIOPHENYLTHIOPYRANE DIOXIDES AS MMP OR TNF-ALPHA INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-20 | — | — | WO | disclosed |
| US-5780473-A | Substituted biphenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-07-14 | — | — | US | disclosed |
| US-5760038-A | Substituted biphenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-06-02 | — | — | US | disclosed |
| WO-1998004260-A1 | SUBSTITUTED BIPHENYL SULFONAMIDE ENDOTHELIN ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-02-05 | — | — | WO | disclosed |
| US-5714496-A | TREATMENT OF HYPERCHOLESTEROLEMIA AND ATHERSCLEROSIS | ZENECA LIMITED (GB) | 1998-02-03 | — | — | US | disclosed |
| EP-0656897-B1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LTD (GB) | 1998-01-07 | — | — | EP | disclosed |
| EP-0725067-A1 | Substituted biphenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-08-07 | — | — | EP | disclosed |
| EP-0656897-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1995-06-14 | — | — | EP | disclosed |
| WO-1994005660-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1994-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10892419-B2 | Space-through charge transfer compound, and organic light emitting diode and display device using the same | NLRP1, NLRP3, CYBA | ATM 1902/4885NPC1 1662/4885NFKB1 2053/4885 |
| US-20200331906-A1 | COMPOUND, METHOD OF SYNTHESIZING COMPOUND WITH PYRIDINE RING AND LIGHT-EMITTING ELEMENT | SUN2, NFE2L2, NR2E3 | ATM 1629/4885NPC1 1988/4885NFKB1 700/4885 |
| US-20230019129-A1 | HEPATITIS B CORE PROTEIN ALLOSTERIC MODULATORS | HAVCR2, MAVS, FABP1 | ATM 3527/4885NPC1 953/4885NFKB1 1667/4885 |
| US-10947224-B2 | Hepatitis B core protein allosteric modulators | HAVCR2, MAVS, FABP1 | ATM 3527/4885NPC1 953/4885NFKB1 1667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.