Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.35 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL16466051 | 0.82 | HCAR2 (0.34) | HCAR2POLBKDM4EARRAB9A | |
| SCHEMBL167789 | 0.81 | — | — | |
| SCHEMBL7892975 | 0.78 | — | — | |
| Bromide SCHEMBL11861598 | 0.78 | — | — | |
| Ammonia Solution, Strong SCHEMBL16039940 | 0.78 | — | — | |
| Carbamic Acid SCHEMBL16465857 | 0.77 | L3MBTL1 (0.43) | KDM4EALDH1A1RAB9ANPC1LMNA | |
| SCHEMBL15635351 | 0.76 | CYP1A2 (0.33) | HCAR2POLBKDM4EARRAB9A | |
| Carbamic Acid SCHEMBL7251118 | 0.74 | ACHE (0.54) | HCAR2POLBALOX15ALDH1A1F7 | |
| Carbamic Acid SCHEMBL782968 | 0.74 | ACHE (0.54) | HCAR2POLBALOX15ALDH1A1F7 | |
| Carbamic Acid SCHEMBL8573342 | 0.74 | ACHE (0.54) | HCAR2POLBALOX15ALDH1A1F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906566-B1 | PROCESS FOR MAKING THIENOPYRIMIDINE COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2016-08-24 | — | — | EP | claimed |