Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Edetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | EYA2 | O00167 | 1/20 | 0.67 |
| ▸ | APP | P05067 | 1/20 | 0.67 |
| ▸ | ACE | P12821 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 3/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.64 |
| ▸ | DRD1 | P21728 | 1/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | DRD3 | P35462 | 1/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Edetic Acid SCHEMBL7033909 | 1.00 | TDP1 (0.67) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL28673728 | 0.98 | TDP1 (0.64) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL1125702 | 0.98 | TDP1 (0.64) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL28856674 | 0.98 | TDP1 (0.64) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL8780347 | 0.96 | TDP1 (0.61) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL9797852 | 0.95 | TDP1 (0.67) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL8008457 | 0.93 | TDP1 (0.64) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL2768272 | 0.93 | TDP1 (0.70) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL333283 | 0.93 | TDP1 (0.70) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL12275304 | 0.92 | TDP1 (0.56) | TDP1EYA2APPACEBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 374 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110567947-A | Kit for detecting activity of phosphatidized recombinant human superoxide dismutase | 北京泰德制药股份有限公司 | 2019-12-13 | — | — | CN | claimed |
| CN-103114128-A | Novel high-resolution quantitative multicolor fluorescent in-situ hybridization method and application thereof | INST OF HEMATOLOGY & BLOOD DISEASES HOSPITAL CHINESE ACADEMY OF MEDICAL SCIENCE & PEKING UNION MEDIC | 2013-05-22 | — | — | CN | claimed |
| US-7011975-B1 | Methods and materials for identifying novel pesticide agents | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2006-03-14 | — | — | US | claimed |
| CN-115948396-B | Glutamate dehydrogenase promoter mutant and application thereof | 中国科学院天津工业生物技术研究所 | 2024-07-09 | — | — | CN | disclosed |
| WO-2024124041-A1 | MULTIPLEXED DETECTION OF NUCLEIC ACID TARGETS | ADVANCED CELL DIAGNOSTICS, INC. (US) | 2024-06-13 | — | — | WO | disclosed |
| CN-114630909-B | Cyclic RNA, vaccine containing same and kit for detecting novel coronavirus neutralizing antibody | 苏州科锐迈德生物医药科技有限公司 | 2024-05-28 | — | — | CN | disclosed |
| EP-4361268-A1 | MDH GENE-BASED POLYNUCLEOTIDE HAVING PROMOTER ACTIVITY AND USE THEREOF | Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences (CN) | 2024-05-01 | — | — | EP | disclosed |
| CN-117721235-A | Gene film chip detection method for simultaneously detecting dendrobium candidum, dendrobium huoshanense and common counterfeit products thereof | 台州市食品药品检验研究院 | 2024-03-19 | — | — | CN | disclosed |
| US-20240084314-A1 | MDH GENE-BASED POLYNUCLEOTIDE HAVING PROMOTER ACTIVITY AND USE THEREOF | TIANJIN INSTITUTE OF INDUSTRIAL BIOTECHNOLOGY, CHINESE ACADEMY OF SCIENCES (CN) | 2024-03-14 | — | — | US | disclosed |
| EP-4331631-A1 | CHIMERIC PEPTIDE-MODIFIED SIS MEMBRANE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Beijing Biosis Healing Biological Technology Co., Ltd. (CN) | 2024-03-06 | — | — | EP | disclosed |
| CN-117487824-A | Artificial expression regulatory element and application thereof | 中国科学院天津工业生物技术研究所 | 2024-02-02 | — | — | CN | disclosed |
| US-5273883-A | Mixing with a sequence-specific oligonucleotide probe complementary to the variant sequence defining the C allele | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |
| WO-1993023574-A1 | POLYMERASE CHAIN REACTION ASSAYS FOR MONITORING ANTIVIRAL THERAPY | KOZAL MICHAEL J (US) | 1993-11-25 | — | — | WO | disclosed |
| CN-1073484-A | The method and the reagent that are used for HLA class I DNA typing | HOFFMANN LA ROCHE (CH) | 1993-06-23 | — | — | CN | disclosed |
| US-5219726-A | Arranging multiple cosmid clones, pooling, synthesizing RNA probes from DNA inserts, hybridizing, identifying, repeating | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1993-06-15 | — | — | US | disclosed |
| EP-0540997-A1 | Methods and reagents for HLA class I DNA typing | F. HOFFMANN-LA ROCHE AG (CH) | 1993-05-12 | — | — | EP | disclosed |
| EP-0514534-A1 | METHODS AND REAGENTS FOR HLA DRBETA DNA TYPING | F. HOFFMANN-LA ROCHE AG (CH) | 1992-11-25 | — | — | EP | disclosed |
| EP-0512342-A2 | Methods and reagents for gamma-globin typing | F. HOFFMANN-LA ROCHE AG (CH) | 1992-11-11 | — | — | EP | disclosed |
| WO-1992010589-A1 | METHODS AND REAGENTS FOR HLA DRBETA DNA TYPING | F. HOFFMANN-LA ROCHE AG (CH) | 1992-06-25 | — | — | WO | disclosed |
| US-4883761-A | Pertussis toxin gene: cloning and expression of protective antigen | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1989-11-28 | — | — | US | disclosed |