Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Edetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | EYA2 | O00167 | 1/20 | 0.70 |
| ▸ | APP | P05067 | 1/20 | 0.70 |
| ▸ | ACE | P12821 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | DRD1 | P21728 | 1/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | DRD3 | P35462 | 1/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Edetic Acid SCHEMBL2768272 | 1.00 | TDP1 (0.70) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL651320 | 0.98 | TDP1 (0.67) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL9797852 | 0.93 | TDP1 (0.67) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL167796 | 0.93 | TDP1 (0.67) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL7033909 | 0.93 | TDP1 (0.67) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL28856674 | 0.91 | TDP1 (0.64) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL8008457 | 0.91 | TDP1 (0.64) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL1125702 | 0.91 | TDP1 (0.64) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL28673728 | 0.91 | TDP1 (0.64) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL15400433 | 0.89 | TDP1 (0.61) | TDP1EYA2APPACEBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113800654-A | Oil removal, water purification, scale inhibition and corrosion inhibition integrated agent and preparation method thereof | 大连理工大学盘锦产业技术研究院 | 2021-12-17 | — | — | CN | claimed |
| CN-110952118-A | Cyanide-free copper plating solution for ceramic circuit, preparation method and electroplating process | 中电国基南方集团有限公司 | 2020-04-03 | — | — | CN | claimed |
| US-20230085615-A2 | ENGINEERED T CELLS AND METHODS OF PRODUCING THEREOF | NANJING LEGEND BIOTECH CO., LTD. (CN) | 2023-03-16 | — | — | US | disclosed |
| CN-113045239-B | Plasticity-maintaining concrete glue reducing agent and preparation method thereof | 广西科达新材料集团有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-113231387-B | Chemical method for lossless recovery of fiber optical element | 云南北方驰宏光电有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-111472006-B | Cleaning composition for carbon steel pipeline of nuclear power fire-fighting water system and preparation method thereof | 苏州热工研究院有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-114822911-A | Conductive powder and preparation method thereof | 武汉北辰星高新材料科技有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114789248-A | Multi-metal core-shell structure nano material based on multi-complexing agent and preparation method thereof | 广东工业大学 | 2022-07-26 | — | — | CN | disclosed |
| EP-4022044-A1 | ENGINEERED T CELLS AND METHODS OF PRODUCING THEREOF | Nanjing Legend Biotech Co., Ltd. (CN) | 2022-07-06 | — | — | EP | disclosed |
| EP-4022041-A1 | NEF-CONTAINING T CELLS AND METHODS OF PRODUCING THEREOF | Nanjing Legend Biotech Co., Ltd. (CN) | 2022-07-06 | — | — | EP | disclosed |
| CN-114616323-A | T cells comprising NEF and methods for producing same | 南京传奇生物科技有限公司 | 2022-06-10 | — | — | CN | disclosed |
| WO-2005021795-A1 | NUCLEOTIDE SEQUENCES SPECIFIC TO BRUCELLA AND METHODS FOR THE DETECTION OF BRUCELLA | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-03-10 | — | — | WO | disclosed |
| WO-2004106553-A2 | NUCLEOTIDE SEQUENCES SPECIFIC TO YERSINIA PESTIS AND METHODS FOR THE DETECTION OF YERSINIA PESTIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2004-12-09 | — | — | WO | disclosed |
| WO-2004013357-A2 | NUCLEOTIDE SEQUENCES SPECIFIC TO FRANCISELLA TULARENSIS AND METHODS FOR THE DETECTION OF FRANCISELLA TULARENSIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2004-02-12 | — | — | WO | disclosed |
| US-6177612-B1 | NUCLEOTIDE SEQUENCES ASSOCIATED WITH BINDING NUCLEAR PROTEINS; FOR TRANSFORMING MONOCOTYLEDONOUS CROP PLANTS AND STABILIZATION OF TRANSGENE EXPRESSION | HER MAJESTY THE QUEEN IN RIGHT OF CANADA, AS REPRESENTED BY THE DEPARTMENT OF AGRICULTURE AND AGRI-FOOD CANADA (CA) | 2001-01-23 | — | — | US | disclosed |
| EP-0414870-B1 | NITRATE REDUCTASE AS MARKER FOR ACRREMONIUM CHRYSOGENUM | GLAXO GROUP LTD (GB) | 1998-09-09 | — | — | EP | disclosed |
| US-5302527-A | Nitrate reductase as marker for filamentous fungi | GLAXO GROUP LIMITED (GB) | 1994-04-12 | — | — | US | disclosed |
| WO-1992016180-A2 | DETECTION OF 3'-AZIDO-3'-DEOXYTHYMIDINE RESISTANCE | SISKA DIAGNOSTICS, INC. (US) | 1992-10-01 | — | — | WO | disclosed |
| US-5010017-A | Process for the immunological quantitative determination of T3 and/or T4 thyroid hormones, using thyroglobulin | COMPAGNIE ORIS INDUSTRIE S.A. (FR) | 1991-04-23 | — | — | US | disclosed |
| US-4966838-A | Process for the immunological quantitative determination of T3 and/or T4 thyroid hormones, using thyroglobulin | COMPAGNIE ORIS INDUSTRIE S.A. (FR) | 1990-10-30 | — | — | US | disclosed |