SCHEMBL16780591

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16780589	1.00	HIF1A (0.48)	HIF1ACA1CA2POLBKMT2A
	SCHEMBL17024693	0.90	LOXL2 (0.46)	HIF1ACA1CA2POLBKMT2A
	SCHEMBL17024692	0.90	LOXL2 (0.46)	HIF1ACA1CA2POLBKMT2A
	SCHEMBL15637757	0.86	HIF1A (0.53)	HIF1APOLBKMT2AALDH1A1SMN1; SMN2
	SCHEMBL17031938	0.86	HIF1A (0.50)	HIF1APOLBKMT2AALDH1A1MEN1
	SCHEMBL12686673	0.86	LOXL2 (0.50)	HIF1APOLBKMT2AALDH1A1CYP4A11
	SCHEMBL17024594	0.84	CA1 (0.48)	CA1CA2POLBKMT2ACYP4A11
	SCHEMBL17024591	0.84	CA1 (0.48)	CA1CA2POLBKMT2ACYP4A11
	SCHEMBL17024561	0.78	LMNA (0.56)	CA1CA2POLBKMT2AALDH1A1
	SCHEMBL17024559	0.78	LMNA (0.56)	CA1CA2POLBKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.